Associate Principal Scientist, Continuous & Expression Technologies; Downstream - Onsite

Position: Associate Principal Scientist, Continuous & Expression Technologies (Downstream) - Onsite
* As an impactful contributor, shape and realize innovation across biologics’ pipeline, strategy, and science
* Advance best science incorporation into pipeline by collaborating with cross-functional teams, from Research & Manufacturing, in a fast-paced, multidisciplinary environment
* Lead development of robust and scalable technologies for downstream processes for biologics
* Identify areas for downstream process innovation/intensification and expand our technologies toolbox to address challenges at different stages of development (clinical, process characterization and commercialization)
* Contribute to strategic initiatives; partner with senior leaders to set overall project strategy, and guide teams towards its execution
* Conceptualize, plan, and execute projects with effective organizational, prioritization and problem-solving skills
* Stay abreast of scientific and regulatory landscape; actively present (premier conferences), publish (peer-reviewed journals) and patent
* Serve as Subject Matter Expert for intensified and/or continuous bioprocessing
* Mentor and actively share expertise; guide career development; build strong, collaborative teams
* Strong fundamental knowledge and subject matter expertise in downstream process development
* Experience in continuous biomanufacturing and experimentation with integrated purification steps
* Expertise in independently conducting and directing the design, execution, analysis, and documentation of all stages of downstream process development
* Track record of accomplishments in downstream bioprocessing with a history of peer-reviewed publications and presentations
* Adaptability and agility to prioritize and deliver complex objectives, often on tight timelines, in a rapidly changing environment
* Experience and aptitude to lead, work, and collaborate in internal and external cross-functional, matrixed teams
* Action-oriented, mindset for creativity; ability to take initiative, innovate, iterate, and problem-solve
* Demonstrated commitment to coach and mentor staff to maximize talent development and utilization
* Excellent interpersonal and communication skills
** PREFERRED EXPERIENCE &

SKILLS:

*
* * Excellent interpersonal and communication skills
* Experience with purification steps integrated with process-analytical technologies
* High-throughput experimentation, automation, and process control
* Experience with single-pass ultrafiltration and in-line diafiltration
* Experience with high throughput experimentation using automation platforms such as TECAN
* Experience using and/or programming process control systems such as Delta

V or PCS 7
* Experience with multi-column chromatography systems (BioSMB, PCC, or similar)
* Experience with statistical data analysis tools and design of experiments (JMP, Design Expert)
* Experience with multivariate data analysis, machine learning, artificial intelligence
* Experience with process modeling packages such as Bio Solve Process, gPROMS, Super Pro Designer, or similar
** Los Angeles Residents Only:
** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
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