Principal Scientist – Multiscale Separations Team Lead

We are seeking a Principal Scientist to join our Separations Sciences team, within the Analytical Enabling Capabilities Organization, located in Rahway, New Jersey.

Scientific Leadership and Laboratory Delivery

• Serve as a recognized subject matter expert in purification and separation sciences, providing scientific leadership and contributing to purification and analytical activities that enable the development pipeline.
• Provide technical leadership and expertise in chromatographic purification, analytical separations, impurity isolation, and related technologies, while guiding resolution of complex scientific and operational challenges.
• Foster a culture of scientific excellence, operational efficiency, safety, and quality throughout laboratory operations.

Capability Development and Innovation

• Partner with DSCS digital technologies (DDT) to drive and implement innovative technologies, laboratory informatics platforms, automation-enabled purification workflows, and digital capabilities that enhance the effectiveness, efficiency, and impact of Separation Sciences capabilities.
• Establish best practices, drive continuous improvement initiatives, and contribute to capability roadmaps aligned with CMC needs.

Talent development and Mentorship

• Partner with the Director of Separation Sciences to identify, recruit, mentor, and develop scientists and laboratory staff, building both technical expertise and leadership capability across the organization.
• Foster a collaborative, inclusive, and high-performing environment that supports employee development, succession planning, and scientific excellence.

Cross-Functional Collaboration and Influence

• Partner closely with key partners in Process Chemistry, Pharmaceutical Analytical Sciences, Automation, Informatics, IT, and other research functions to support project progression and capability development.
• Serve as a trusted scientific partner to project teams, contributing purification and analytical expertise to project strategy and departmental initiatives.

Operations and Infrastructure Leadership

• Partner in laboratory operations, instrumentation strategy, capital planning, and implementation of automation and digital solutions that improve scientific productivity.
• Partner with Facilities, Procurement, Engineering, IT, and external vendors to ensure reliable laboratory operations, regulatory compliance, and continuous capability advancement.

External Scientific Engagement

• Maintain awareness of emerging technologies and scientific advances in separation sciences and chromatography, contributing to our company's scientific reputation through publications, presentations, collaborations, and external engagement.

• Ph.D. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline with a minimum of 8 years of relevant industrial experience in pharmaceutical, biotechnology, or related drug development and research environment.
• M.S. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline with 10-12 years of relevant industrial experience in a pharmaceutical, biotechnology, or related drug discovery research environment.

• Extensive experience in chromatographic purification and analytical separations supporting drug development programs, with expertise in HPLC, uHPLC, LCMS, SFC, and preparative chromatography technologies.
• Working knowledge of orthogonal detection technologies, including PDA, Multi-angle light scattering, charged aerosol detection etc.
• Demonstrated hands-on experience delivering purification solutions across a broad range of scales (µg to kg), enabling seamless translation from early-stage experimentation through larger-scale execution.
• Demonstrated experience supporting multiple therapeutic modalities, including small molecules, peptides, adjuvants, and other emerging modalities.
• Demonstrated ability to provide scientific leadership, influence technical direction, and deliver results through a laboratory-based scientific capability, including scientific leadership in chromatography, separation sciences, analytical chemistry.
• Experience implementing new technologies, laboratory informatics platforms, LIMS solutions, automation-enabled purification workflows, digital workflows, instrumentation, and process improvements.
• Experience mentoring, and developing scientific staff,…