Vice President, Compliance

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

Reporting to the Vice President, US Compliance, this role will support Rev Med’s U.S. business. This role will lead the strategy, development, and execution of the company’s U.S. healthcare compliance program, ensuring all activities are conducted ethically and in accordance with applicable laws, regulations, and industry codes. This executive will be instrumental in shaping and sustaining a culture of integrity as the company advances and commercializes its oncology pipeline.

This attorney is responsible for program design, operational implementation, monitoring, and enforcement - while working in close partnership with the Healthcare Law team to deliver coordinated, risk‑based guidance to internal business partners across the organization.

• Design, implement, and continuously improve a comprehensive U.S. healthcare compliance program consistent with OIG Guidance, PhRMA Code, and applicable industry standards.
• Establish and maintain policies, procedures, and systems to ensure compliant operations across all U.S. commercial, medical, and research activities.
• Provide regular compliance updates to executive leadership, including risk assessments, metrics, and remediation plans.
• Serve as the company’s U.S. Compliance Officer and key representative in interactions with regulators, external counsel, and industry associations.
• Coordinate compliance guidance and initiatives with ex‑US compliance teams.

• Partner closely with the Healthcare Law team to ensure consistency between legal interpretation and compliance operations.
• Maintain a clear functional separation of responsibilities between Compliance and Healthcare Law.
• Collaborate to deliver integrated, practical guidance to internal clients — particularly within Commercial, Medical Affairs, Clinical Development, and Market Access functions.

• Provide compliance leadership for all U.S. programs, including those involving targeted therapies, precision medicine, and molecular diagnostics.
• Oversee compliance in complex scientific collaborations — including investigator-sponsored trials (ISTs), research collaborations, and co‑promotion or data‑sharing arrangements.
• Ensure compliant governance of interactions with oncology healthcare professionals (HCPs), key opinion leaders (KOLs), and academic research centers.
• Oversee U.S. aggregate spend, transparency, and Sunshine Act reporting obligations, including oncology-specific speaker programs, congress sponsor ships, and advisory boards.
• Provide compliance support for patient access programs, patient support services, and specialty distribution channels, ensuring compliant interactions with patients, caregivers, and advocacy groups.

• Develop and implement risk-based compliance training for field and headquarters staff, tailored to oncology business activities (e.g., clinical data dissemination, compassionate use programs).
• Design and oversee monitoring and auditing plans covering commercial field conduct, grants, consulting arrangements, and medical education.
• Lead investigations into potential violations, ensuring timely, thorough resolution and corrective actions.
• Track, analyze, and report compliance metrics and trends to management and governance bodies.

• Serve as a trusted advisor to senior leadership and cross‑functional teams on compliance risks and mitigation strategies.
• Collaborate with Legal, Medical Affairs, Clinical Operations, and Market Access on…