Medical Director

Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.

Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.

What Matters to Us

Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.

Arcellx Core Values

• Start with authenticity:
  We foster an inclusive environment where each person can bring their authentic self to work.
• Think ‘we’ before ‘me’:
  We prioritize collective success, collaborating and supporting one another to achieve our shared goals.
• Embrace the challenge:
  We deliver exceptional results by working with shared determination and a commitment to doing what’s right.

How You’ll Make a Difference

As a medical director at Arcellx, you’ll provide strategic oversight to clinical development programs across indications from early to late-stage development. Your medical leadership will help advance our therapies to patients in need.

The “Fine Print” – What You’ll Do Clinical Development Strategy

• Contribute to the development and implementation of clinical development plans for cell therapy programs.
• Provide medical oversight and strategic input into study design, protocol development, and endpoint selection.

Medical Monitoring and Safety Oversight

• Serve as the medical lead for clinical trials, including oversight of patient safety and adverse event management.
• Collaborate with clinical operations and pharmacovigilance teams to ensure effective medical monitoring and risk management.

Regulatory Interactions and Submissions

• Interface with regulatory authorities on clinical development plans, study protocols, and data submissions.
• Contribute to the preparation of regulatory documents (e.g., IND/IMPD, BLA/MAA) and responses to inquiries.

Clinical Data Analysis and Interpretation

• Analyze clinical trial data, interpret results, and contribute to the development of clinical study reports and publications.
• Work closely with biostatistics and data management teams to ensure robust data analysis and reporting.

Key Opinion Leader Engagement

• Collaborate with external experts, investigators, and advisory boards to gather insights and support clinical trial execution.
• Represent the company at scientific conferences, symposia, and external meetings.

Cross-functional Collaboration

• Partner with translational research, manufacturing, and regulatory affairs teams to integrate medical insights into program strategies.
• Collaborate with business development and commercial teams to support product positioning and market access strategies.

Skills and Experience We Look For

• Medical Doctor (M.D.) or non-US equivalent of M.D. degree with hematologic malignancy experience in an academic or hospital environment. Completion of a residency program and oncology focused subspecialty fellowship strongly preferred.
• 5+ years of relevant clinical trial experience in the pharmaceutical industry, academia, or equivalent, including:
  • Regulatory submission support
  • Medical writing oversight for trial related documents
  • Strategic vision including understanding of the field, knowledge of competitive landscape, and network of academic investigators.
• Well-honed communication skills with the ability to collaborate effectively with cross-functional teams.
• Must possess excellent oral and written English communication skills.
• Demonstrated success addressing complex problems and creating solutions for one or more programs.
• Proven leadership skills with the ability to influence and guide decision making…