Chief Commercial Officer

Location:

Redwood City, California

Rezolute is a late-stage rare disease company focused on significantly improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Our antibody therapy, RZ358 (ersodetug), is designed to treat all forms of HI and has shown substantial benefit in clinical trials and real-world use for the treatment of congenital hyperinsulinism (cHI) and tumor hyperinsulinism (tHI). We are planning to announce topline results for a Phase 3 study for cHI in December 2025 and a Phase 3 study for tHI will commence in Q3 2025 with anticipated topline results in 2H 2026.

Reporting to the Chief Executive Officer, the CCO will work closely with the CEO and other members of the leadership team to shape and execute the company’s strategy and priorities for growth. This is an exceptional opportunity to play a key role on the management team, including leading the commercial activities globally with an anticipated launch for ersodetug in 2027.

Rezolute is seeking an experienced CCO capable of providing leadership, direction and vision with the aptitude to drive commercial growth and excellence. The CCO will be responsible for all commercial operations as well as the go-to-market strategy for product launches and commercialization while managing all aspects of the commercial team. The CCO must be a dynamic leader who will be tasked with establishing and overseeing the successful direction, planning and execution of company policies, objectives, initiatives and deliverables.

Additional responsibilities include:

• Driving prelaunch plans and the go-to-market strategy, ensuring alignment to support the growth plan and revenue targets as well as collaboration across the enterprise to ensure successful product commercialization.
• Defining and implementing the commercial strategy, including working with other members of the leadership team to identify challenges, opportunities, and action plans to ensure the achievement of commercial objectives.
• Supporting the CEO and the rest of the leadership team in the development and execution of a corporate strategic plan.
• Formulating Rezolute’s strategic direction in collaboration with the leadership team including identifying opportunities for growth, market expansion, and competitive advantage.
• Setting clear commercial goals and objectives that are aligned with the company’s vision.
• Remaining informed about market trends, industry developments, and competitive landscape.
• Conducting market research and analysis to identify opportunities for business growth and recommend potential modifications to Rezolute’s strategy accordingly.
• Capturing market facts/dynamics and reports to support KOL and patient engagement as well as competitive readiness.
• Leading and further developing the commercial team including creating a world class commercial organization.

The CCO is expected to have strong commercial, marketing and business development expertise, combined with the ability to succeed at a strategic, tactical and operational level, with excellent global experience and cultural sensitivity. The CCO must have outstanding internal and external communication skills and an inclusive pro-active approach.

• Bachelor's degree in business administration, Marketing, Finance, or a related field. Master's in Business Administration (MBA) is preferred with a minimum of 15 years of experience in global executive roles in the biopharmaceutical industry, ideally leading commercial and business development go-to-market teams.
• Extensive knowledge of drug development generally and commercial execution specifically. Experience in rare, ultra rare and orphan disease therapies is required, including recent experience in leading successful rare disease product launches.

Rezolute (RZLT) currently anticipates the base salary for the Chief Commercial Officer role could range from $380,000 to $450,000 and will depend, in part, on the successful candidate’s geographical location and their qualifications for the role, including education and experience. This position will also be eligible for an annual performance bonus in accordance with the terms of…