Sr. Manager Solution Prep

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Sr. Manager Manufacturing - AR5 Solution Prep

What you will do

Let’s do this. Let’s change the world. In this vital role you will lead the Solution Preparation organization within AR5 — a critical and highly integrated part of Amgen’s large-scale biomanufacturing network. This team plays an essential role in the success of the plant by supplying high-quality media to Cell Culture and buffers to Purification, enabling the reliable and consistent manufacture of Amgen’s biologic medicines.

The Senior Manager oversees a team of more than 50 staff working across four shifts, each led by a Front-Line Manager, ensuring safe, compliant, and efficient 24/7 operations.

As a member of the AR5 Manufacturing Leadership Team, this leader shapes operational performance, drives site-wide alignment, and plays a key role in transforming how we manufacture today to deliver on the processes of tomorrow.

Key Responsibilities:

Safety and Quality Leadership

• Champion Amgen’s core commitment to safety and product quality by fostering a culture of accountability and continuous improvement.
• Ensure manufacturing execution consistently meets GMP, EHS, and regulatory expectations, with proactive risk identification and mitigation.
• Strengthen and build upon an already strong safety and quality culture, reinforcing standards through daily leadership presence on the floor (Gemba).

Operational Leadership

• Lead the Solution Preparation organization to achieve production goals across a 24/7 operation.
• Provide oversight and direction to Front-Line Managers, ensuring alignment with AR5’s Floor Operating Principles and site objectives.
• Coordinate cross-functional support to troubleshoot and resolve operational challenges, including participation in the AR5/AR30 on-call leadership rotation.

Strategic and Continuous Improvement

• Influence site and network-level manufacturing strategy, driving operational excellence, digital literacy, and adoption of modern manufacturing processes.
• Lead initiatives to reduce deviations, enhance process reliability, and improve right-first-time performance.
• Champion digital and data-driven solutions to improve decision-making, operational transparency, and real-time performance oversight.

Innovation and Process Enhancement

• Drive process transformation efforts that enhance efficiency and eliminate non-value-added activities.
• Lead operational readiness for process improvements, including innovative changeover, scheduling, and resource deployment solutions.
• Support I-530 operations, capacity utilization, and scalability across both AR5 and AR30.

Talent Development

• Mentor and grow Front-Line…