Post Doctoral Fellow - Quantitative Systems Pharmacology; QSP

Post Doctoral Fellow - Quantitative Systems Pharmacology (QSP) Description

Boehringer Ingelheim is seeking an enthusiastic, creative, and highly motivated Postdoctoral Fellow to join the Clinical Pharmacology Group in the Clinical pharmacology and Non-clinical safety science (CPS) Department at our US headquarters in Ridgefield, CT. The Ridgefield campus, along with our sister sites in Texas and California, includes a thriving community of postdocs and PhD students that connects globally with their peers on our European campuses.

As a Postdoctoral Fellow, you will be responsible for conducting independent research under the direct guidance of an experienced QSP expert and further supported by a team of experts committed to your success. You will interact with a diverse range of individuals (including mentors, fellow researchers, students, and collaborators from global Clinical Pharmacology and CPS department as well as other departments), and help to foster a collaborative research environment that facilitates exchange of knowledge and ideas.

Your research will be focused on scientific questions and new methodologies in the field of QSP that align with the goals of the department and contribute to Boehringer-Ingelheim’s innovative and growing pipeline. You will be expected to present your work to internal leadership and, ultimately, publish your findings in leading journals within the field. Postdoctoral Fellowships are three-year positions, with a potential one-year extension.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies´ success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance.

Our competitive compensation and benefit programs reflect Boehringer Ingelheim´s high regard for our employees.

With support from their advisor and team, the ideal candidate is expected to:

• Design and conduct their own independent research project(s).
• Collaborate with other researchers within and outside Boehringer Ingelheim.
• Effectively communicate and defend their own work in the context of team and department goals, both orally and in writing.
• Establish an international reputation in your area of expertise with publications and conference participation at national and international events.

The responsibilities also include:

• Apply quantitative systems pharmacology (QSP) modeling, to integrate in vitro and in vivo nonclinical and clinical data for predicting pharmacodynamics of new therapeutic modalities in the field of inflammation, oncology, cardiovascular, renal and metabolic diseases, CNS, retinopathies and emerging areas.
• Identify the dynamic interactions between a drug and pathophysiology to understand the system at the cellular and biochemical network levels, and to connect the pharmacokinetics with drug efficacy and safety after drug administration in the clinical setting.
• Communicate and present findings.
• Utilize appropriate data analysis techniques and visualization tools.
• Contribute to informed decision-making and strategy for clinical drug development.
• Interpret and communicate results to an interdisciplinary audience and experts in the field.

• Ph.D. degree in related discipline with no more than three (3) years of Post Doctoral experience.
• Extensive experience in area of scientific expertise in QSP modeling platforms (e.g., R, Matlab, Julia).
• In-depth knowledge of pharmacokinetic processes and the impact of physiological parameters.
• Basic knowledge of drug development, ADME, systems biology/physiology and pathophysiology.
• Creativity and innovation in driving cutting-edge research with a strong publication record.
• Ability to independently conduct a research project and effectively communicate the results.
• Strong teamwork skills with independent working style, high level of initiative, reliability and readiness to take on responsibility.
• Ability to optimize and develop assays/techniques, as well as leverage new technology opportunities to address scientific questions.
• Exceptional writing, presentation, and communication skills.
• Ability to comply with all applicable regulators, performing all work in a safe manner; maintain proper records in accordance with SOP's and policies.

• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required).
• Must be 18 years of age or older.

This position offers a base salary of $80,000.00 USD. For an overview of our benefits please .