Computational Antibody Repertoire Analysis Co-Op

Are you passionate about computational immunology and applying immune repertoire science to improve biotherapeutic discovery efficiency? As a Computational Antibody Repertoire Analysis Co-Op in Biotherapeutics Research, you will actively participate in an ambitious project that will build a state-of-the-art NGS computational pipeline that will enable prioritization of antibody hits to decrease non-binder and low affinity binder attrition. You will learn to use somatic hypermutation models to infer B cell evolutionary trajectories and predict the most evolved clones within clonotype families from immune repertoires deriving from BI's humanized mouse model.

You will work with BI scientists to benchmark computational models and help develop a reproducible pipeline that enriches for likely antigen binders and ranks higher-affinity candidates within expanded clonotype families. This role offers hands-on experience with single-cell and bulk immune-repertoire data, antibody lineage analysis, model evaluation, scientific software development, and translation of computational results into experimentally testable hypotheses.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunities for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance.

Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Are you passionate about computational immunology and applying immune repertoire science to improve biotherapeutic discovery efficiency? As a Computational Antibody Repertoire Analysis Co-Op in Biotherapeutics Research, you will actively participate in an ambitious project that will build a state-of-the-art NGS computational pipeline that will enable prioritization of antibody hits to decrease non-binder and low affinity binder attrition. You will learn to use somatic hypermutation models to infer B cell evolutionary trajectories and predict the most evolved clones within clonotype families from immune repertoires deriving from BI's humanized mouse model.

You will work with BI scientists to benchmark computational models and help develop a reproducible pipeline that enriches for likely antigen binders and ranks higher-affinity candidates within expanded clonotype families. This role offers hands-on experience with single-cell and bulk immune-repertoire data, antibody lineage analysis, model evaluation, scientific software development, and translation of computational results into experimentally testable hypotheses.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunities for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance.

Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

• Curate, quality-control, and analyze antibody repertoire…