Call Expression of Interest MSCA Postdoctoral fellowships at UNIGE – N. Hybrid Brain

Position: Call for Expression of Interest for MSCA Postdoctoral fellowships at UNIGE – N. 52 Hybrid Brain[...]
Department of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS)
Description - Call for Expression of Interest for a joint application under the upcoming Call for MSCA Postdoctoral Fellowships 2026
University of Genoa, UNIGE, located in Genoa, ITALY, welcomes postdoctoral researchers of any nationality, with an excellent track record, to apply to the European Commission Marie Sklodowska-Curie (MSCA) Postdoctoral Fellowships 2026. Our University has been beneficiary of several MSCA-PF in Horizon 2020 and Horizon Europe.
The Marie Sklodowska Curie (MSCA) Postdoctoral Fellowship is one of funding scheme of the European Commission’s Horizon Europe Research & Innovation programme, dedicated to excellent research promoting international mobility, as well as interdisciplinary and intersect oral exchanges.
MSCA fellowship grant provides a competitive salary plus mobility and family allowances if applicable, as well as a contribution to cover research, training and networking costs. The research projects will have 2- or 3-years duration.
Selected candidates will be provided with special support for proposal writing and development.
The University of Genoa will organize in May the fifth edition of the Masterclass MSCAected candidate researchers will have the opportunity to attend a 2-days online intensive training and coaching course on how to write a successful proposal. This masterclass is a pathway of support to candidates and their supervisors in preparing project proposal, including prescreening activity of the draft proposals and the organisation of dedicated B2B meetings, by the European Research Office of Uni Ge, National Contact Point and other experts.
The masterclass will take place in May 2026.
MSCA domain:
Information Science and Engineering (ENG)
Research Project Description
This project lies at the intersection of computational neuroscience, in vitro human neurobiology, digital health, and precision medicine, with a strong emphasis on integrated Biological–Digital Twin approaches. The thematic focus is the development of patient-specific digital twins of neuronal networks and brain activity to mechanistically link molecular and cellular alterations to network dynamics in genetic epilepsy.
The research combines advanced computational modeling, biophysically grounded network simulations, machine learning–based simulation-based inference, and EEG signal modeling with experimental data derived from hiPSC-based in vitro neuronal networks and clinical electrophysiological recordings. A distinctive feature of the project is the closed-loop integration between patient-derived in vitro systems (including MEA-based electrophysiology) and mechanistic digital twins, enabling the inference and experimental validation of candidate cellular and synaptic mechanisms underlying pathological brain activity.
A central objective is the translation of molecular- and network-level information obtained in vitro into brain-scale predictions, thereby enabling individualized and mechanistically informed interpretation of disease phenotypes and treatment response. The candidate will gain hands‑on experience in experimental data integration, electrophysiological signal analysis, and advanced computational modeling within a translational framework.
The project offers a highly interdisciplinary and international training environment, bridging computational modeling, human stem‑cell–derived neuronal systems, electrophysiology, and digital twin technologies. It is particularly suited for candidates with a strong background in computational neuroscience, applied mathematics, physics, bioengineering, who are motivated to work at the interface of quantitative modeling, human in vitro systems, and translational neuroscience.
Research Group
The Neuroengineering Genoa Group is a multidisciplinary research unit within the Department of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa. The group operates at the interface of neuroengineering, computational neuroscience, and translational brain technologies, combining experimental and computational approaches to investigate brain…