Associate Director, Supply Chain Planning & Procurement

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late‑stage biotechnology company redefining the transplant process by developing next‑generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.

With our purified, high‑precision investigational cell therapies we hope to not only replace patients’ blood and immune systems with healthy ones, but also restore their lives.

We have built a state‑of‑the‑art, 100,000‑square‑foot manufacturing facility in Sacramento, CA (7910 Metro Air Pkwy) to ensure the consistent and reliable delivery of our high‑precision cell therapy products. This site is essential to advancing our clinical pipeline and supporting future commercial availability of our life‑saving therapies.

The Associate Director, Supply Chain Planning leads planning and procurement functions while driving the design, implementation and optimization of manufacturing execution systems (MES) and enterprise resource planning connections across cell therapy manufacturing sites. This role ensures robust, compliant and scalable planning and procurement processes with digital systems to enable accurate, real‑time visibility and uninterrupted production of clinical and commercial cell therapy products.

The associate Director will partner with Manufacturing, Finance IT, Facilities and Quality to deliver a reliable planning foundation that supports operations and data‑drive decision‑making.

• Production Associates:
  Must have visual acuity of 20/20 (corrected or uncorrected) and normal color vision to safely perform critical tasks such as visual inspection of materials, equipment, and labeling, including distinguishing color‑coded components in a GMP environment.
• Must be able to meet cleanroom gowning requirements, including wearing full gowning (face coverings, gloves, hoods, goggles) for extended periods, as needed. Use of cosmetics (makeup, painted nails), jewelry, or facial piercings is not permitted in the cleanroom, and any skin conditions that cause shedding must be disclosed.

• Must be able to work at either Orca Bio Sacramento location (3400 Business Dr. or 7910 Metro Air Pkwy) based on operational needs.
• Must be comfortable regularly participating in video‑based meetings.
• May be required to work scheduled overtime, weekends, or holidays based on business needs.

• Lead site supply planning, production scheduling, and material planning to meet customer service and operational targets.
• Manage production and material capacity planning aligned with clinical and commercial demand forecasts, developing and analyzing operational scenarios to support capacity and demand needs.
• Ensure effective inventory strategies to maintain optimal raw material, consumable, and finished product levels.
• Develop Sales & Operations Planning (S&OP) processes for cell therapy programs across internal manufacturing sites.
• Facilitate relationships with internal commercial stakeholders and suppliers and vendors, where appropriate.

• Serve as site business lead for MES and ERP system deployment, configuration, and optimization.
• Partner with IT, Engineering, and other functions to define requirements, ensure seamless integration, and enable end‑to‑end planning functionality.
• Translate planning processes into digital workflows, ensuring master data accuracy, transactional discipline, and real‑time visibility.
• Drive user adoption, training, and change management for MES/ERP solutions at the site.

• Implement best practices in supply chain planning, leveraging system capabilities to improve forecast accuracy, scheduling efficiency, material availability, and cost competitiveness.
• Establish KPIs and dashboards for planning performance, leveraging ERP/MES data for decision‑making.
• Identify and resolve systemic bottlenecks in planning processes through digital…