Chemical Process Engineer

Chemical Process Engineer

Company: Kelly Science, Engineering, Technology & Telecom

Location: St. Louis, Missouri

Employment type: Contract to Hire – intended to start as a contractor with the goal of becoming a full‑time permanent employee within six months.

We are looking for an experienced Chemical Engineer who can support the setup of small molecule pharmaceutical processes, including equipment specification, interlinking, control system identification, and technology transfer to a contract manufacturing site.

• Scale‑up & tech transfer:
  Convert lab procedures to scalable unit operations (reaction, crystallization, filtration, drying), author and execute transfer packages and PPQ protocols.
• Continuous manufacturing:
  Develop, implement, and optimize continuous processes for small‑molecule APIs, ensuring robustness and regulatory compliance.
• Equipment design & scale:
  Evaluate, design, and/or identify appropriate scalable equipment for lab, pilot, and commercial applications; partner with engineering to ensure fit‑for‑purpose systems.
• Validation & compliance:
  Lead and author process validation documents, batch records, change controls; investigate deviations/OOS and drive CAPA.
• Cross‑functional collaboration:
  Work closely with R&D/Analytical, QA/QC, Supply Chain, and external customers to meet timelines and CQA/CQPs.
• Documentation:
  Write SOPs, reports, and technical summaries suitable for regulatory inspections.

• BS in Chemistry, Chemical Engineering or a related discipline.
• 3–7 years in GMP small‑molecule API manufacturing/scale‑up.
• Background in bench chemistry with strong understanding of reaction mechanisms, impurity control, and crystallization science.
• Solid grasp of cGMP, data integrity, and regulatory expectations; strong technical writing skills.
• Hands‑on experience with continuous manufacturing approaches and equipment design/selection for scale‑up strongly preferred.

• The role focuses on the development side of tech transfer, ensuring processes and equipment are correct for scaling up from bench to pilot scale.
• Ideal candidate has pharmaceutical industry experience (chemistry) and pilot‑scale operations, bridging bench‑scale and large manufacturing.
• GMP knowledge is helpful but not a firm requirement; nuances can be quickly learned.
• The employer is a non‑profit entity in St. Louis dedicated to delivering U.S.–made active pharmaceutical ingredients.

Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce.

Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of California’s state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E‑Verify and will provide the federal government with your Form I‑9 information to confirm that you are authorized to work in the U.S.