Postdoctoral Research Associate; Proteomics and Multi-omics in Neurodegeneration - Psychiatry

Position: Postdoctoral Research Associate (Proteomics and Multi-omics in Neurodegeneration) - Psychiatry
Location: St. Louis

Postdoctoral Research Associate (Proteomics and Multi‑Omics in Neurodegeneration) – Psychiatry

The Cruchaga lab at WashU Medicine is recruiting multiple Postdoctoral Research Associates. The lab generates and analyzes high‑throughput multi‑omic data to study neurodegeneration and central nervous system diseases, with an emphasis on Alzheimer’s disease, Parkinson’s disease, and other dementias. The ultimate goal is to understand disease biology, define novel biomarkers, and identify therapeutic targets. We pioneer the integration of genetics with omic data to identify proteomic signatures and develop predictive models for Alzheimer’s, Parkinson’s, and Dystonia, as well as to discover novel proteins and pathways implicated in disease pathogenesis.

We are currently analyzing brain, CSF, and blood samples using transcriptomics, proteomics, metabolomics, and other omics to identify biomarker candidates and druggable targets.

Primary

Duties & Responsibilities

• Analyze plasma, CSF, and brain proteomic and metabolomic data.
• Identify biomarkers using machine‑learning approaches.
• Integrate multi‑omics data with genomics, transcriptomics, and methylomics.
• Generate novel insights into neurodegeneration in a multidisciplinary and collaborative environment.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards. You must be physically able to wear protective equipment and to provide standard care to research animals.

Salary

Base pay is commensurate with experience.

Education &

Required Qualifications

Ph.D., M.D., or equivalent terminal or doctoral degree.

• Ph.D. qualification in Genetics, Bioinformatics, Computer Science, Data Science, Statistical Genomics, or a related discipline involving interrogation of ‘omics’ datasets.
• Hands‑on experience with large‑scale human omics studies is expected.

Preferred Qualifications

• Skilled in at least one programming language (R, Python, or Perl) and experience with Linux and/or high‑performance cluster environments.
• Strong analytical reasoning to extract biological insights from data‑driven approaches.
• Familiarity with publicly available resources beneficial.

Skills & Certifications

No specific certifications or work experience are required for this position.

Driver’s License

A driver’s license is not required.

Work Experience

Research experience (1 Year) and postdoctoral experience in Genetics, Biochemistry, Molecular Biology, Cell Biology, or a related field (1 Year).

Questions & Accommodation

For frequently asked questions about the application process, refer to our Postdoctoral Resources. If you are unable to use our online application system and require accommodation, email Candidate Questions or call 314‑935‑1149 and leave a voicemail with the nature of your request.

Pre‑Employment Screening

All external candidates receiving an offer will be required to submit to pre‑employment screening, including criminal background check, drug screen, employment and education verification, physical examination, and required vaccinations. All offers are contingent upon successful completion of screening.

Benefits Statement

Washington University in St. Louis offers a comprehensive benefits package. Eligibility is subject to employment status and workload. For details, visit (Use the "Apply for this Job" box below)..

EEO Statement

Washington University in St. Louis is committed to equal employment opportunity and encourages applications from underrepresented groups. The university’s policy provides equal opportunity and access to all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity, disability, veteran status, or genetic information.

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