Manager, Infrastructure Engineering

Tiger Bio Sciences is seeking a hands-on, operationally focused Manager, Infrastructure Engineering to lead the day-to-day operation, security, and reliability of our enterprise infrastructure. This role is responsible for the network, wireless, and Microsoft Azure cloud environments that support all Tiger Bio Sciences facilities, as well as the daily execution of cyber operations, including security monitoring, incident response, and vulnerability remediation.

The Manager serves as the primary day-to-day point of contact for our external cyber security advisory partner and ensures our infrastructure remains secure, resilient, and compliant as the organization grows through product launches, facility expansion, and M&A activities.

• Manage the daily operation, configuration, and maintenance of enterprise network infrastructure, including firewalls, routers, switches, and wireless access points across all facilities.
• Administer and optimize the Microsoft Azure cloud environment, including virtual networks, compute, storage, identity (Microsoft Entra ), and backup services.
• Maintain network segmentation, access control, VPN, and secure remote access solutions in line with security and regulatory requirements.
• Monitor infrastructure availability, performance, and capacity, and proactively identify and resolve issues before they impact the business.
• Lead patching, firmware updates, and lifecycle management for infrastructure hardware and software.
• Maintain backup, disaster recovery, and business continuity capabilities, including periodic recovery testing.
• Plan and execute network and infrastructure buildouts for new facilities, expansions, and acquired businesses.
• Maintain accurate network diagrams, configuration baselines, asset inventory, and operational runbooks.
• Support Azure cost management and Fin Ops practices, including resource right-sizing and usage reporting.

• Oversee daily security monitoring and triage of alerts from SIEM, EDR/XDR, firewall, and cloud security tools.
• Lead incident response activities, including detection, containment, eradication, recovery, and post-incident review, and maintain incident response playbooks.
• Manage the vulnerability management program, including scanning, risk-based prioritization, remediation tracking, and reporting to leadership.
• Serve as the primary day-to-day point of contact for the external cyber security advisory partner, coordinating monitoring, escalations, threat intelligence, and remediation activities.
• Support the operation of the Cyber Threat Operations Center and the continuous improvement of detection and response capabilities.
• Implement and enforce security hardening standards (e.g., CIS Benchmarks) across network, server, endpoint, and cloud environments.
• Support internal and external audits, cyber insurance requirements, and risk assessments by providing evidence and completing remediation actions.
• Support cyber awareness training and phishing simulation programs.

• Execute infrastructure changes in accordance with ITIL change management processes and controlled documentation practices.
• Partner with IT Quality to ensure infrastructure supporting GxP systems is qualified, documented, and maintained in a validated state.
• Maintain a working knowledge of FDA 21 CFR 1271, FDA 21 CFR 820, FDA 21 CFR Part 11, AATB standards, ISO standards, cGMP/CGTP, other relevant regulations/standards, and internal organizational policies and standard operating procedures.

• Manage relationships with infrastructure vendors, carriers, and service providers, and support budgeting, procurement, and contract renewals.
• Report infrastructure and security metrics, risks, and KPIs to the Director, Enterprise Technology and IT leadership.
• Participate in an on-call rotation and respond to outages and security incidents outside of normal business hours as needed.
• Travel domestically up to 20% to support multi-site operations, facility buildouts, and integration activities.
• Perform other duties as assigned.

• 5+ years of experience in IT infrastructure or network engineering, with at least 3 years in a leadership or senior technical lead capacity.
• Hands-on experience managing enterprise firewalls (e.g., Palo Alto, Fortinet, Cisco), routing and switching, and enterprise wireless networks.
• Demonstrated experience administering Microsoft Azure infrastructure and…