Senior​/Lead Bioinformatics Scientist; Epigenomics

Senior/Lead Bioinformatics Scientist (Epigenomics)

Natera is currently seeking a Senior/Lead Bioinformatics Scientist to join our Bioinformatics Research Team focused on Epigenomics in Oncology. Natera’s mission is to change the management of disease worldwide by using information gained from a simple blood draw to detect disease early and proactively inform treatment.

• Design, implement, and validate innovative algorithms and statistical methods to analyze large‑scale data sets related to cancer detection.
• Foster a culture of innovation, collaboration, and scientific excellence.
• Work closely with molecular biologists and clinical scientists to solve challenging problems.
• Contribute to experimental design and ensure data integrity and quality control.

• PhD in Bioinformatics, Computer Science, Statistics, or a related field with a strong emphasis on cancer epigenomics.
• Proven track record of developing state‑of‑the‑art computational methods for high‑throughput sequencing data processing.
• Strong foundation in quantitative reasoning, statistical analysis and applied machine learning.
• Strong computational and programming skills, with hands‑on experience with Python and its scientific library stack (Pandas, Num Py, scikit‑learn).
• Experience using Linux command‑line tools and writing shell scripts.
• Ability to perform hypothesis‑driven research, visualize findings and summarize results in oral and written form.
• High scientific rigor and eagerness to teach and learn about new computational methods and biology.

Compensation Range: $146,900—$183,600 USD (base salary). Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program:

• Annual performance incentive bonus.
• Long‑term equity awards.
• Comprehensive health benefits (medical, dental, vision).
• 401(k) with company match.
• Generous paid time off and company holidays.
• Additional wellness and work‑life benefits.

Natera™ is a global leader in cell‑free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

Competitive Benefits:
Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401(k) benefits, commuter benefits and more. We also offer a generous employee referral program.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.