Senior Biostatistician; Oncology Clinical Studies

Position: Senior Biostatistician (Oncology Clinical Studies)
This is an exciting opportunity for a Senior Biostatistician to support the adoption of Natera’s oncology portfolio of innovative molecular diagnostic tests. You will contribute to the design, analysis, and reporting of oncology clinical trials while working closely with senior team members. You will assist in developing appropriate study designs and help generate insights that support the broader oncology portfolio.

The ideal candidate brings deep statistical expertise, strong scientific communication skills, and experience with applied statistics in a fast-paced, collaborative environment.

PRIMARY RESPONSIBILITIES:

Study Design and Statistical Strategy:
Support the statistical design for oncology clinical utility studies. Provide technical expertise in complex study design methodologies and data analyses. With guidance, propose and justify efficient study designs tailored to complex oncology use cases.

Cross-Functional Collaboration:

Serve as study statistician for multiple studies. Collaborate with clinical, medical, and translational partners to influence study planning, development, and execution. Documentation and Reporting:
Author and review high-quality statistical deliverables, including statistical analysis plans (SAPs), and reports (TLFs, CSRs, publications) for cross-functional collaborators and stakeholders. Innovation and Improvement:
Recommend and apply novel statistical approaches where appropriate. Support continuous improvement of departmental processes, tools, and templates to enhance team efficiency and knowledge.  Collaborate on manuscripts for publications.

QUALIFICATIONS:

Advanced degree in Biostatistics, Statistics, or a related quantitative field (Ph.D. preferred).0-2+ years of experience in clinical trial biostatistics.

Expertise in time-to-event analysis, including handling of censoring, competing risks, and advanced survival modeling approaches commonly used in oncology.

Proficient in R.KNOWLEDGE, SKILLS, AND ABILITIES:
Demonstrated ability and enthusiasm for working in fast-paced, cross-functional environments with collaborators from diverse technical backgrounds.

Ability to communicate complex statistical concepts clearly to both technical and non-technical audiences.

Preferred qualifications:

Expertise with innovative study design (e.g. adaptive and biomarker-informed designs), power calculations, and endpoint evaluation.

Working knowledge of ICH and GCP guidelines as well as CDISC standards (e.g. SDTM, ADaM).

Experience with non-inferiority studies.

Compensation & Total Rewards This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of  hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:

Annual performance incentive bonus

Long-term equity awards

Comprehensive health benefits (medical, dental, vision)401(k) with company match

Generous paid time off and company holidays

Additional wellness and work-life benefits

Compensation Range $130,700—$163,400 USDOUR OPPORTUNITYNatera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera,…