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Manager, Data Science

Listing for: Natera
Full Time position Listed on 2026-11-11

Job Description & How to Apply Below

POSITION SUMMARY:

Natera is a global leader in cell-free DNA testing, advancing diagnostics in oncology, women’s health, and organ health to support better patient care. As a Data Science Manager in R&D Operations, you will lead a team of data scientists to design and implement data solutions to accelerate R&D  will take ownership of operational data workflows, establish scalable processes and SOPs, and apply ML and/or AI expertise to enable informed decision-making and drive efficiency.

You will work closely with our Data Engineering Manager and Data Analytics Manager to deliver integrated, reliable data solutions across the team.

RESPONSIBILITIES:
Direct, mentor, and develop a team of data scientists, including hiring, performance management, and career development

Set the technical direction for the data science team and advance its ML/AI capabilities

Own the data science roadmap for R&D Operations, define success metrics, and report progress and status to R&D Operations and executive stakeholders

Translate pain points and opportunities surfaced by data analytics into solutions–process changes, algorithms, or new tools–and drive their implementation to deliver measurable process improvement, championing efficiency gains in turnaround time and cost per activity across R&D Operations Own the sample governance process end-to-end, ensuring accuracy, timeliness, and accountability, and manage the associated stakeholder relationships

Develop and oversee machine learning models, optimization strategies, and AI solutions to forecast demand, optimize resource allocation, and automate operational processes

Lead the development of new data products, as well as the training and enablement around them to grow visibility, self-service, and data-driven decision-making across R&D Operations Design, document, and implement processes for data governance, data integrity, and reproducibility across R&D Operations Partner with the Data Engineering and Data Analytics Managers and collaborate cross-functionally across R&D and supporting functions to translate business needs into governed, reliable data solutions

Write clear, testable requirements (e.g. acceptance criteria, data contracts) and define the path from prototype to production in partnership with Data Engineering

QUALIFICATIONS:

7+ years of experience in data science in biotechnology, life sciences, or operations research

Demonstrated people-management experience, including hiring, mentoring, and developing data scientists through coaching on performance and career growth

Experience owning a data science roadmap and communicating progress to senior and executive stakeholders

Working knowledge of a relevant scientific or operational domain–biology or life sciences strongly preferred, operations research a close second–sufficient to partner effectively with R&D Operations stakeholders

Experience working with laboratory or operational data (e.g., laboratory informatics management system (LIMS), sample management, inventory, purchasing/procurement, or equipment operations)
Track record of driving process improvement–identifying root causes and delivering solutions through process changes, algorithms, or new tools

Strong background in building data processes, SOPs, and governance frameworks

Expertise in Python (including pandas, scikit-learn, Tensor Flow/PyTorch) and SQLHands-on expertise in machine learning and/or AI applied to real-world problems, setting technical direction for predictive modeling and optimization solutions

Experience taking ML models or data products from prototype to production, including monitoring and maintenance

Experience with modern cloud data warehouse and transformation tooling (e.g. Snowflake, dbt)
Experience partnering with peer…
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