Research Associate, Entry Level; Molecular Cloning, In Vivo

Research Associate, Entry Level (Molecular Cloning, In Vivo)

Base pay range: $70,000.00/yr – $85,000.00/yr

Engage Bio is a preclinical‑stage biotechnology company pioneering the next generation of genetic medicines. Our Tethosome platform combines the potency and safety of mRNA with the durability of DNA, delivering long‑lasting, non‑viral gene expression. This enables the body (e.g., liver or lung) to produce therapeutic biologics for extended periods, potentially for years from a single dose. We’re developing treatments for a broad spectrum of diseases, from ultra‑rare genetic disorders to common conditions that affect millions.

Fast‑paced, collaborative, and mission‑driven, our work is rooted in a simple but ambitious goal: the elimination of human disease. If you’re looking for a place where your work can have a meaningful impact early in your career, we’d love to hear from you.

We are seeking a motivated Research Associate to support our scientific team across in‑vivo and cell‑based activities. This role is ideal for a recent graduate with laboratory experience or an individual with 1–2 years of industry or academic research experience.

This is a great opportunity to gain broad exposure to early‑stage biotech R&D, including programs ranging from early conception to IND‑enabling stages.

Position type:
Full‑time (Monday through Friday), on‑site (San Carlos, CA).

Our lab is located at MBC Biabs, San Carlos and offers state‑of‑the‑art scientific instruments, a fully stocked kitchen, regular scientific talks/events, team lunches twice a week, a dynamic community of biotech scientists and innovators, happy hours, and ping‑pong tournaments.

• Bachelor’s degree in the sciences.
• Recent graduate with some laboratory experience, or 1–2 years of industry or academic research experience.
• In‑vivo work (IP/IV injections, blood draws).
• PCR.
• Molecular cloning (e.g., Gibson or Golden Gate assembly).
• Bacterial or mammalian cell culture.
• DNA purification.
• Chromatographic purification of biomolecules.
• High‑throughput assays/pipetting (96‑ or 384‑well).
• mRNA synthesis and lipid nanoparticle formulations.
• Maintaining a clean and organized lab environment.
• Maintaining records of batches of reagents used in experiments.

• Base salary $70,000–$85,000 per year (depending on experience).
• Significant equity compensation.
• Performance‑based bonus.
• Full health, dental, and vision insurance.

If you’re passionate about making a difference through science—and ready to learn fast and contribute to something meaningful—we’d love to meet you. Please send your resume and a short cover letter outlining your interest and relevant experience.

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