Sr. Principal Medical Development Director

Help us change lives

At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.

The Sr. Principal Medical Development Director will be responsible for clinical and translational leadership in the development and execution of the company’s oncology strategies; including, but not limited to, the design and implementation of next-generation sequencing (NGS) based assays focused on the development, validation, and regulatory approval of diagnostic tests designed to help determine the most appropriate therapies for patients, monitor therapy effectiveness, and detect the presence of residual disease.

In partnership with Portfolio Lifecycle Management and Strategy, this role will provide oncology leadership during the design, development, and implementation of studies that support pipeline products and/or line extensions to on-market products. The Sr. Principal Medical Development Director will develop external relationships with leaders in academic oncology, cooperative trial groups, and research organizations, as well as identify investigators and sites to participate in clinical trials and inform medical strategies.

The Sr. Principal Medical Development Director will initiate and lead external ad boards involving medical leaders in pharma, key opinion leaders, and other third parties. The Sr. Principal Medical Development Director will be responsible for the review, interpretation, and leadership in the report of key study results and will also help design and implement the medical support for all new or extended precision oncology tests and services.

The Sr. Principal Medical Development Director will be both a leader of and participant on internal cross-functional program teams and working groups including, but not limited to, members of the business development, research and development, pathology and clinical lab operations, biostatistics, clinical affairs, medical affairs, regulatory, market access, and commercial teams. This position will also provide medical leadership across Precision Oncology as a member of the medical organization.

This position can be based in Redwood City, CA, or be field based.

• Develop the overall vision and strategy for one or more specific Exact Sciences’ Precision Oncology (PO) products, including, but not limited to, the Oncotype DX recurrence score, radiation score, and colon recurrence score;
  Onco Ex Tra  and therapy selection portfolio; and the molecular residual disease (MRD) liquid biopsy portfolio, in partnership with internal and cross-functional stakeholders including commercial, pipeline, compliance, and regulatory.
• Identify opportunities to expand indications for existing Exact Sciences’ PO products and new products within the pharma space.
• Collaborate with Exact Sciences’ cross-functional team members from the research and development, pipeline, and commercial organizations to participate in and provide medical expertise to the formulation of commercialization strategy and the creation of product profiles for new products and services.
• Participate as the medical monitor on study teams and lead the development of clinical protocols required to support product development, validation, and commercialization; including, but not limited to, the adoption and development of novel approaches for the demonstration of clinical validation and utility.
• Engage with medical leaders within precision and molecular, medical and surgical and radiation oncology to gain a greater understanding of key clinical questions in patient management, requisite a new generation of clinical tool needs, and facilitate their understanding of the scientific validity and clinical utility of Exact PO products.
• Accountable for scientific presentations and publications generated as a result of PO product development collaborations.
• Provide oncology expertise and clinical…