Scientific Associate Director – Toxicology

Working with Us

Bristol Myers Squibb offers work that is challenging, meaningful and life‑changing. At BMS, the day‑to‑day work is anything but routine—whether it’s optimizing a production line or pioneering breakthroughs in cell therapy, the impact is real, transforming patients’ lives and the careers of those who contribute. Unlock your potential with high‑achieving teams and opportunities that scale beyond ordinary expectations.

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Nonclinical Safety (NCS) within Nonclinical Research and Biotherapeutics designs and implements the overall nonclinical safety strategy to support development, marketing approval and post‑marketing safety of BMS’s portfolio in oncology, hematology, cardiovascular disease, fibrosis, immunology and neurology. NCS members work at sites in New Brunswick, Lawrenceville, Princeton, NJ;
San Diego, Brisbane, CA;
Cambridge, Mass;
Seattle, WA, collaborating with discovery, development, health authorities and partners worldwide to bring innovative medicines to patients globally. Level depends on experience.

• Responsible for oversight of nonclinical safety evaluation programs for selected drug candidates.
• Design and report toxicity studies (GLP/non‑GLP), including single‑ and repeat‑dose toxicity, investigative toxicity, and other required studies.
• Act as a Nonclinical Safety representative on early‑ and late‑stage project development teams.
• Provide scientifically and strategically sound nonclinical development plans to management and development teams.
• Interact on an as‑needed basis with regulatory agencies worldwide on non‑clinical safety evaluation issues.
• Write and critically review submission documents—CTD sections for INDs and NDAs, IBs, PIPs, briefing books—to support clinical trials and drug registration globally.
• Participate in discussions with internal development teams and/or regulatory agencies to address safety findings and provide safety assessments.
• Evaluate, propose and apply new scientific methodology to enhance scientific excellence and/or productivity in Nonclinical Safety. Work collaboratively across disciplines to identify, characterize and resolve target/compound based toxicities.
• Represent BMS in external scientific and regulatory collaborations, committees and consortia.
• Gain broad‑based exposure to the various functional areas within Nonclinical Safety with an opportunity to perform independent research as appropriate.
• Collaborate with the Discovery organization to help evaluate toxicity of drug candidates.
• Ensure compliance with Good Laboratory Practice, Standard Operating Procedures and study protocols in conducting nonclinical studies. Ensure compliance with all company/departmental policies, especially those related to animal welfare and safety.
• Embrace and demonstrate BMS Core Values to create an atmosphere of scientific excellence, open communication and creativity that maximizes productivity.

• Bachelor’s Degree and 15+ years of academic/industry experience
• Master’s Degree and 12+ years of academic/industry experience
• PhD and 8+ years of academic/industry experience

Plus 6+ years of leadership experience.

• 10+ years regulatory toxicology/development experience.
• Knowledge of biochemical and mechanistic toxicology, immunology, pharmacology, biology of disease, and/or experimental pathology. Experience designing and interpreting in vitro and in vivo studies exploring mechanisms of toxicology involving biochemical, immunological, functional, molecular and/or structural endpoints.
• Effective written and oral communication skills, especially as they pertain to writing clear, accurate documents and presenting data.
• Ability to manage multiple research activities, provide and accept input on data interpretation, foster teamwork and work well with others.
• Ability to interpret and apply available toxicity data to assess relative risk or hazard to humans.

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