Sr Manager, Enterprise Business Systems

JOB SUMMARYWe are seeking an experienced and results-driven Sr Manager, Enterprise Business Systems to join our growing IT team. This role will oversee the implementation, configuration, maintenance, and support of business-critical applications across the organization, with primary focus on the systems that run our General & Administrative (G&A) functions:
Finance and Accounting, People/HR, Legal and Compliance, and Facilities, IT Operations, and Business Operations.

The Sr. Manager, Enterprise Business Systems will collaborate with leaders across each G&A function to optimize workflows, troubleshoot system issues, and drive continuous improvement in business processes. This role ensures that business applications operate efficiently, securely, and meet the evolving strategic and tactical needs of the company.

This position will be based out of our San Diego Headquarters.

KEY RESPONSIBILITIES Apply deep working knowledge of enterprise software across the G&A landscape to implement, integrate, and maintain business applications supporting:

Finance and Accounting (ERP, budget forecasting & tracking, procurement, invoicing & expenses),People/HR (HRIS, payroll, talent acquisition, learning management)
Legal and Compliance (contract lifecycle management, e-signature, entity management)
Facilities/Operations (service management, asset and space management).Ensure application security, role-based access controls, segregation of duties, and compliance with company policies across all G&A systems.

Perform regular system updates, patches, and upgrades to maintain performance and security.

Liaise with software vendors and service providers for application support and upgrades.

Integrate business applications with other systems and third-party tools and assist in data migrations, imports, and exports between systems.

QUALIFICATIONS Bachelor’s degree in Information Technology, Computer Science, Business Administration, or a related field.
12 years IT experience, with 8+ years administering cross-functional business applications spanning multiple G&A functions, life sciences experience preferred

Experience supporting financial processing and audit controls for Sarbanes-Oxley compliance, as well as the access, confidentiality, and retention requirements of HR and Legal systems.

Working knowledge of data privacy and associated regulatory requirements such as GDPR, CCPA, HIPAA, and Transparency Reporting.

Strong experience implementing, maintaining and improving Finance, Procurement, HR, Legal and Compliance systems such as Net Suite, Adaptive, Procurify, HRIS, Ashby ATS, Docu Sign, and Ironclad preferred

Experience managing SaaS vendor relationships, contracts, renewals, and license optimization across a portfolio of business applications.

Experience in system implementation, data migration, or process automation.

Excellent communication and collaboration abilities with strong analytical and problem-solving skills.

Prior experience with IT service management, identity and access management (SSO, SCIM, provisioning), and corporate IT or facilities systems preferred

Experience with reporting methodologies and business metrics preferred

Project management experience or certifications (e.g., PMP, ITIL, Agile) preferred ABOUT IAMBIC THERAPEUTICS Iambic Therapeutics (Nasdaq: IAM) is a technology and clinical-stage life sciences company headquartered in San Diego. By utilizing molecular superintelligence — integrating proprietary AI with automated, scalable chemistry and biology experimentation — our platform is designed to address the totality of drug discovery and development. At Iambic, we are building an engine that is designed to power the future of medicine.

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