Scientist II

HC Biosciences, Inc. (San Diego), a WuXi App Tec Company, is expanding its in vitro Pharmacology. We’re seeking a highly skilled and motivated Scientist II to lead assay development projects and support target discovery and validation efforts for the HTS and assay screening group.

• Works on routine assignments per written procedures, with ability to recognize deviation from accepted practice.
• Receives minimal instructions on routine work and detailed instructions on new assignments.
• Works under close supervision from supervisor or senior personnel.
• Performs support functions (e.g., Runner function) in the specified department.
• Works in a team environment and independently as required.
• Might be required to work holidays, weekends, and overtime as necessary.
• Contributes to overall operations and departmental goals.
• Performs job-specific tasks in compliance with applicable regulations, international standards, and WuXi App Tec policies and SOPs.
• Has thorough understanding of GLP and GMP.
• Other duties as assigned, including assistance to other departments.

• Design, implement, and perform projects for functional assay development.
• Hands‑on experience with cell‑based assays and biochemical assays.
• Independently develop and perform assays to evaluate biologic drug targets and candidates (GPCR, ion channels, enzymatic assays, kinase assays, etc.).
• Develop assays in biochemical and cell‑based formats suitable for SAR screening in 96‑ or 384‑well formats.
• Deep understanding of molecular biology and cell biology with experience in mammalian cell culture and compound handling techniques.
• Experience with luminescence, fluorescence, absorbance, and radiometric detection preferred.
• Scientific creativity, critical thinking, and fast‑learning capabilities.
• Industrial drug R&D experience a plus.
• Effective communication with internal team colleagues and external clients to promote world‑class services.

• 5–10 years of relevant experience or equivalent.
• Master’s or PhD preferred in Biochemistry, Biotechnology, or Molecular Biology.
• Strong understanding of complex scientific procedures with technical proficiency in molecular and cell biology.
• Industry experience in Pharma/Biotech or exposure to R&D processes preferred; prior CRO commercial experience considered a strength.
• Outstanding written and oral communication skills and interpersonal skills for a teamwork‑driven environment.

• Proficient oral and written communication skills.
• Ability to read, write, and understand English (Mandarin).
• Proficient in Microsoft Office (Excel, Word, Outlook).
• Travel required X%, domestic/international, daily/overnight.

• Work in office environment with minimal noise.
• Work in lab setting with exposure to animals/biohazards/chemicals.
• No animal allergies to applicable species.
• Wear appropriate PPE.
• Work in variable noise levels.
• Stand, sit, or walk for long periods.
• Lift up to 10 lbs routinely.
• Crouch, bend, twist, and reach as necessary.
• Push/pull up to 10 lbs routinely or occasionally.
• Clarity of vision; recognize colors.
• Perform repetitive motions.
• Climb ladders, stairs, scaffolding.
• Work in variable temperatures from high to freezing.
• Indoor/outdoor working conditions.

Anticipated salary range: $80,322 to $104,000.

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job‑related duties as requested by Management.