Biostatistician II

Biostatistician IIThe USC Keck School of Medicine, Epstein Family Alzheimer’s Therapeutic Research Institute (ATRI), located in San Diego, California, is an academic institute focused on advancing the development of treatments for Alzheimer’s disease (AD) and related dementias through innovative clinical trials. The ATRI Biostatistics Section provides statistical leadership for clinical trials and studies managed by ATRI.We are seeking a highly trained and motivated Biostatistician II with strong statistical, programming, and scientific communication skills who is interested in building a career in clinical trials biostatistics in an academic research environment.

This position is suited to a biostatistician with prior clinical research experience who can contribute with a high degree of technical independence while working as part of an experienced and collaborative biostatistics team.

The Biostatistician II will join an established group of statisticians and work closely with senior biostatistics staff, biostatistics postdoctoral fellows, faculty biostatisticians, study investigators, and other research collaborators. Under the direction and statistical oversight of senior biostatistics staff and faculty biostatisticians, the Biostatistician II will serve as the lead statistical analyst and manage the day-to-day biostatistical activities for assigned clinical trials and studies.

The individual will serve as the primary biostatistics contact for routine study activities, coordinate statistical deliverables, and provide guidance to junior biostatistics staff working on the study. Senior biostatistics staff and faculty biostatisticians will continue to provide oversight and guidance on study design, statistical strategy, complex methodological issues, and major scientific decisions.

The Biostatistician II will:
• Manage the day-to-day biostatistical activities for assigned clinical trials and research studies under the direction of senior biostatistics staff and faculty biostatisticians.
• Perform and oversee statistical programming and analyses for clinical trials and related research studies.
• Apply appropriate statistical methods to longitudinal and other complex clinical trial and research data.
• Conduct sample size, power, and related design calculations to support clinical trials and research studies.
• Contribute to study design and the development of statistical approaches, including study objectives, endpoints, analysis strategies, and statistical analysis plans.
• Prepare, manage, and evaluate analysis-ready datasets, statistical analyses, tables, figures, and other statistical outputs.
• Coordinate statistical activities and deliverables across assigned studies, including timelines, analyses, quality control activities, and documentation.
• Provide guidance and technical support to junior biostatistics staff working on assigned studies and review their statistical programming and analytical work as appropriate.
• Lead or contribute to quality control and quality assurance of statistical analyses and programming.
• Contribute substantively to statistical methods and results sections for study reports, abstracts, presentations, and scientific manuscripts.
• Communicate statistical concepts, study design considerations, analytical approaches, and results clearly to investigators and multidisciplinary research collaborators.
• Present statistical results in study team meetings and contribute to the interpretation of findings and scientific discussions.
• Develop and maintain an in-depth understanding of assigned clinical trials, including study design, protocol, endpoints, data structure, analysis objectives, and statistical responsibilities.
• Identify statistical or study-specific…