Research Associate II, Analytical Development

Immunity Bio is a vertically integrated commercial stage biotechnology company developing next-generation therapies that bolster the natural immune system to defeat cancers and infectious diseases. The Company’s range of immunotherapy and cell therapy platforms, alone and together, act to drive and sustain an immune response with the goal of creating durable and safe protection against disease. Designated an FDA Breakthrough Therapy, ANKTIVA is the first FDA-approved immunotherapy for non-muscle invasive bladder cancer CIS that activates NK cells, T cells, and memory T cells for a long-duration response.

The Company is applying its science and platforms to treating cancers, including the development of potential cancer vaccines, as well as developing immunotherapies and cell therapies that we believe sharply reduce or eliminate the need for standard high-dose chemotherapy. These platforms and their associated product candidates are designed to be more effective, accessible, and easily administered than current standards of care in oncology and infectious diseases.

• Immunity Bio is developing cutting-edge technology with the goal to transform the lives of patients with cancer and develop next-generation therapies and vaccines that complement, harness and amplify the immune system to defeat cancers and infectious diseases.
• Opportunity to join a publicly traded biopharmaceutical company with headquarters in Southern California.
• Work with a collaborative team with the ability to work across different areas of the company.
• Ability to join a growing company with professional development opportunities.

The Research Associate II, Analytical Development will work as part of the Analytical team to support adoptive cell therapy projects based on our various cell platforms. The position will assist in developing, optimizing and validating bioassays to support cell therapy projects; and will be responsible for supporting the efficient operation of the laboratory and performing scientific studies to support cell therapy projects.

• Perform cell-based assays with minimal supervision to support analytical and process development team.
• Maintain cells as required for various assays.
• Perform cell characterization using Mass Cytometry (Cyt Of), Flow Cytometry, HPLC, and MSD Platform.
• Maintain, calibrate and operate cell analytical equipment and instruments.
• Develop standard operating procedures, analytical test methods, analytical sampling plans and batch records.
• Provide support to cross-functional teams to advance development of cell therapy products.
• Develop or adapt analytical methods for cell therapy products and develop process improvements and efficiencies.
• Design and execute analytical method development and qualification in support of lead candidate selection, process development, product release and stability, and product characterization.
• Design and execute experimental approaches and new analytical technologies and assist with continuous improvement of analytical tools.
• Design and execute experiments to develop, qualify, and transfer cell-based potency methods for the testing and release of pipeline products.
• Provide support to the bioanalytical testing of samples for immunogenicity and biomarkers.
• Performs ad-hoc and cross-functional duties and/or projects as assigned to support business needs and provide developmental opportunities.

Bachelor’s degree with 3+ years of experience in Biology, Biochemistry, Immunology or a related field required; or Master’s degree with 1+ years in Biology, Biochemistry, Immunology or a related field required.

Experience with immunoassay technologies such as, Mass Cytometry (Cyt Of), flow…