Scientist - Lipid Nanoparticle; LNP) Formulation Job San Diego area,California USA,Research/Development

Position: Scientist - Lipid Nanoparticle (LNP) Formulation

Bachelor’s degree in Chemistry, Biochemistry, Chemical Engineering, or a related discipline with 5+ years of biopharma industry experience.
OR a Master’s degree with 2+ years of industry experience.

Education

Bachelor’s degree in Chemistry, Biochemistry, Chemical Engineering, or a related discipline with 5+ years of biopharma industry experience.
OR a Master’s degree with 2+ years of industry experience.

Required Skills

LNP Expertise:
Minimum of 2 years of hands-on laboratory experience specializing in LNP formulation and encapsulation of nucleic acids (mRNA, siRNA, or DNA).
Analytical

Skills:

Proficiency with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays.
Software & Data:
High proficiency in MS Excel is required; hands-on experience with statistical and data analysis software (e.g., JMP, Prism) is preferred.
Core Competencies:

Strong attention to detail, a track record of producing reproducible data, excellent organizational skills, and the ability to communicate effectively within a fast-paced team environment.

Preferred Skills

Prior experience with targeted LNP preparation (mAb, Fab, ScFv, VHH coated LNP) and immune cell delivery is highly desirable.

Summary

We are seeking a motivated and detail-oriented Scientist 1 to join our Formulation team.
In this hands-on laboratory role, you will work closely with senior scientists to execute and optimize the synthesis of targeted and non-targeted lipid nanoparticles (LNPs) for nucleic acid delivery.
The successful candidate will be a collaborative team player with strong technical and data analysis skills who is ready to contribute to our non-viral delivery platform.

Responsibilities

Execute and optimize the formulation and characterization of lipid nanoparticles (LNPs) or targeted lipid nanoparticle (tLNPs) encapsulating nucleic acids for in vitro and in vivo studies under the minor guidance of senior formulation scientists.
Implement Design of Experiment (DoE) based screening campaigns to evaluate and establish optimal LNP compositions and processing parameters.
Collaborate cross-functionally with internal teams to support and fulfill formulation requests.
Support early-stage formulation development and downstream processing activities when needed, including cryoprotection, scale-up, and stability studies.
Maintain detailed records documenting formulation activities and results.
Analyze, interpret, and present experimental data to the formulation team.
Contribute to routine lab management activities, including inventory tracking, supply ordering, buffer preparation, and autoclaving.
** Only those lawfully authorized to work in the designated country associated with the position will be considered.**
** Please note that all Position start dates and duration are estimates and may be reduced or lengthened based upon a client’s business needs and requirements.*
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