Sr. Scientist - Chemical Development

Work Schedule

Standard (Mon-Fri)

Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life – enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life‑changing therapies.

With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full‑time benefits.

This is a fully onsite role based at our customer’s site in San Diego, CA. We welcome applicants from all locations within the US. Please note that relocation assistance is not provided for this position, and any relocation costs will be the responsibility of the candidate.

Must be legally authorized to work in the United States without sponsorship.

Must be able to pass a comprehensive background check, which includes a drug screening.

Coordinates kilo lab operations, chemical manufacture, and site readiness including equipment identification, qualification and maintenance. A partner for scientists in preparing batch records, adapting processes for scale‑up, hands‑on manufacture, engineering solutions required for safe and efficient small molecule and peptide operations. Will also provide support of process development activities and systems development for operations including platforms. Will provide training to junior staff for operations at kilogram scale.

• Assists in all facets of chemical process development from small scale synthesis to scale‑up manufacturing during API development
• Supports the technology transfer (chemical process, analytical methods) for manufacturing activities into the Neurocrine kilo laboratory
• Participates as a key member of cross‑functional development teams to effectively meet science and business‑critical objectives related to API manufacture
• Participates in internal project team meetings ad‑hoc to ensure readiness for internal scale‑up
• Performs authoring and review of manufacturing protocols, reports, and batch records
• Collaborates with multiple functional lines (Pre‑clinical, Clinical, CMC, Regulatory, Quality Assurance, Commercial) within the company
• Provides logistical and scientific support for process development for API projects and projects of limited scope, such as solid‑state form and catalytic process screening as well as new technology endeavors deemed of interest
• Maintains the kilo lab and equipment, serves as an expert in set up and operations
• Other duties as assigned

• Bachelor's degree in lab sciences such as Organic Chemistry, Chemistry or similar
• Sr. Scientist:
  Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years’)
• OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’)
• OR PhD

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Common Knowledge &

Skills:

• Advanced knowledge and demonstrated ability to work with chemical synthetic equipment and execute…