Senior Director, Rewards and HRIS

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN ® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.

Vir Biotechnology has exclusive rights to the universal PRO-XTEN ® masking platform for oncology and infectious disease. PRO-XTEN ® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

Reporting to the CHRO, the Sr Director of Total Rewards and HRIS will lead the design, delivery, and governance of Vir Bio's global compensation and benefits programs. You will also be responsible for the strategy and implementation of HR analytics initiatives and HRIS oversight across the HR function and broader organization.

In this role you will partner with senior business leaders and the HR leadership team to translate business strategy into total rewards strategies that attract, reward, and retain key talent. You will ensure programs are competitive, equitable, and aligned with organizational objectives.

The ideal candidate will be a hands‑on leader with deep compensation and benefits expertise, strong analytical capabilities, and a track record of developing successful strategies. This position requires the ability to balance strategic thinking with tactical execution-conceptualizing innovative solutions while driving day‑to‑day program administration and continuous improvement.

This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.

• Lead the strategic design, implementation, and administration of global compensation and benefits programs, including base pay structures, short-term and long-term incentive plans (including commercial sales incentive plans), recurring compensation cycles, and program targets
• Design and implement benefits programs through needs analysis, competitive benchmarking, and cost-effectiveness evaluation
• Manage annual benefit enrollment, plan changes, wellness initiatives, and compensation planning cycles
• Conduct competitive market analysis to ensure programs remain competitive, equitable, and aligned with business objectives
• Ensure compliance with federal, state, and international compensation and benefits regulations
• Serve as the hands‑on lead for executive compensation, including program design and benchmarking
• Prepare and present analyses and recommendations to senior leadership, the Board of Directors, and the Compensation Committee
• Strategically lead all aspects of management and coordination with the Compensation Committee including meeting planning, deliverable preparation, meeting facilitation, and tracking of follow up actions.
• Align compensation programs with performance management processes to drive accountability and reward performance
• Oversee global mobility programs including immigration and relocation
• Develop and implement HR analytics strategy and provide HRIS oversight to ensure data integrity
• Execute total rewards communication strategies to ensure employees understand and value their compensation and benefits
• Manage a high‑performing team across compensation, benefits, and analytics functions

• BA/BS and 12+ years or MS/MBA and 10+ years of relevant…