Head of AI Alzheimer’s

AI is already changing how people work, learn, and access care. It has the potential to unlock extraordinary benefits—faster medical breakthroughs, accelerated scientific discovery, more personalized services in healthcare and education, new tools for creativity and invention, higher productivity and economic growth, improved public services like transportation systems, and so much more.

But building powerful systems to benefit humanity is only a part of the work of our mission. Advanced AI models will also present new challenges that are already surfacing, and we need to be prepared to identify these challenges and develop solutions to address them.

These are the two dimensions of what we’re building the Foundation to do. We aim to enable the use of AI to find solutions to humanity’s hardest problems, transform what people are capable of, and deliver real benefits in people’s lives—while working hard with partners to be ready for new challenges, and to help make society resilient, as AI advances.

This work is just beginning. Over the next year, as we quickly ramp up, the Foundation expects to invest at least $1 billion across life sciences and curing diseases, jobs and economic impact, AI resilience, and community programs. This includes early investments toward our previously announced $25 billion commitment to curing diseases and AI resilience.

The OpenAI Foundation is building out its Life Sciences and Curing Diseases program to help accelerate progress against the biggest diseases facing humanity. One of the program’s initial focus areas is AI for Alzheimer’s.

Alzheimer’s is one of the hardest and most heartbreaking diseases families face — and one of the toughest problems in medicine. We believe AI has enormous potential to speed scientific and medical progress to save and improve lives, and that AI’s ability to reason across complex data could help researchers uncover new insights in Alzheimer’s disease and related dementias. The Foundation is especially interested in efforts that can help map disease pathways, detect biomarkers for clinical care and clinical trials, and accelerate the personalization of treatments — including, where possible, repurposing existing FDA-approved molecules.

We are looking for a Program Director, AI for Alzheimer’s to help define and build this work from the ground up. This is a founding role within the Foundation’s life sciences program. You will work closely with the Head of Life Sciences and Curing Diseases to shape strategy, identify high-potential opportunities, and help deploy significant resources over time into organizations and initiatives that can materially accelerate progress.

This role requires someone who is highly flexible, thoughtful, and action-oriented — comfortable operating in an ambiguous environment, engaging deeply with external experts and organizations, and translating a broad mission into a focused portfolio of grants and initiatives.

• Develop clear theses for how the Foundation can accelerate progress towards the goal of preventing and treating Alzheimer’s, deploying hundreds of millions of dollars towards that goal over time

• Work closely with the Head of Life Sciences and Curing Diseases to shape strategy, prioritize opportunities, and refine the Foundation’s approach over time

• Source, evaluate, and recommend grants and other funding opportunities. Conduct diligence on organizations, projects, and leaders, including assessing scientific value and potential for real-world impact

• Engage deeply with the external ecosystem, including researchers, nonprofits, public health organizations, startups, academic centers, funders, and other potential grantee organizations

• Build and…