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Senior Platform Engineer, Lab Infrastructure and Security

Job in San Francisco, San Francisco County, California, 94199, USA
Listing for: Plasmidsaurus
Full Time position
Listed on 2026-10-17
Job specializations:
  • IT/Tech
    Systems Engineer, Network Engineer, Cloud Computing: Infrastructure & Operations
Salary/Wage Range or Industry Benchmark: 180000 - 260000 USD Yearly USD 180000.00 260000.00 YEAR
Job Description & How to Apply Below

Plasmidsaurus is on a mission to accelerate new cures and promote a healthier planet by unlocking a new level of productivity for scientists. Our sequencing services are used daily by thousands of innovators, including Nobel laureates, Fortune 100 pharma, and over 70,000 scientists.

We began by revolutionizing plasmid sequencing, making it exponentially cheaper and faster, with innovative sequencing technologies and a global network of laboratories that turn samples into answers in hours, not weeks.

Now we are expanding that same disruptive model across all of genomics. With the launch of our new RNA-seq service, we are taking a bold step toward our vision to sequence everything, providing scientists everywhere with faster, simpler, and more affordable access to the data that powers discovery.

Every team member at Plasmidsaurus plays a crucial role in driving the future of biotech research. Together, we are building the world’s most efficient sequencing engine that operates overnight, scales globally, and helps scientists make breakthroughs faster than ever before.

Role Overview

At Plasmidsaurus, our infrastructure doesn't just run software. It powers the sequencers, robots, and compute systems that help scientists around the world speed up their research and get to breakthrough discoveries faster. We're looking for a Platform Engineer to build and scale the infrastructure behind our 10 labs worldwide. You'll work across networking, hardware, cloud infrastructure, automation, and security, and you’ll have the freedom to architect solutions to complex engineering challenges.

Your work will directly shape how quickly we launch new labs, expand sequencing capacity, and deliver reliable results to scientists solving some of the most important problems in the world.

What You'll Do Architect and Scale Our Global Lab Networks
  • Design and scale the networks powering sequencers, robotics, and compute across our 10 global labs. Own network architecture and reliability, including pf Sense, Mikro Tik, HA firewalls, VLANs, DHCP/DNS, Tailscale, and inter-site connectivity.
  • Architect and deploy networking for new labs and expansions, from rack and switch infrastructure to high-speed 10

    Gb connectivity between sequencers and storage.
  • Automate network provisioning and configuration with Terraform, Ansible, and CI/CD to make infrastructure deployments faster, more consistent, and reliable.
Build Reliable, Scalable Lab Compute Infrastructure
  • Build and improve the infrastructure supporting our production hardware, including Illumina and Oxford Nanopore sequencers, Opentrons robots, lab instruments, GPU clusters, and storage. Own connectivity, observability, and scalability as sequencing capacity grows.
  • Build and maintain secure, automated device identity and access systems using PKI, AWS IAM Roles Anywhere, and SSH.
Engineer Security Into Our Infrastructure
  • Own and strengthen the security of our cloud infrastructure, web applications, and APIs through proactive testing, AI-assisted red teaming, and close collaboration with Product Engineering to resolve vulnerabilities.
  • Build and operate vulnerability management across cloud infrastructure, lab devices, and application dependencies, including scanning, patching, and secrets management.
  • Lead technical security incident response, from detection and containment through resolution and postmortems, continuously improving our ability to prevent and respond to threats.
You are someone who
  • Loves solving hard infrastructure problems, especially where hardware, networking, and software intersect.
  • Thinks like a builder. You automate repetitive work, improve the systems you inherit, and enjoy taking projects from design through production.
  • Has deep technical curiosity and enjoys…
Position Requirements
10+ Years work experience
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