Executive Director, Global Commercial Lead

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Revolution Medicines is a clinical‑stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

Reporting to the VP, Global Commercial Development Disease Area Lead, this newly created role will serve as a leader for continuing to build our global oncology marketing capabilities driving global commercial strategy at product team and overseeing global launch strategy and lifecycle planning for a given indication/indications. Candidates should be passionate about leading cross‑functional collaboration, and contributing as both a strategic leader and hands‑on driver in a growing organization.

This position is primarily remote with travel required for scientific and team meetings.

• Partner across the company including with clinical development, medical affairs, market access, to drive indication strategy, shape brand strategies across the product team.
• Ensure global readiness to drive successful launch planning, commercialization, and performance tracking across the U.S. and key ex‑U.S. markets.
• Execute global disease area strategy, brand strategies, including branding, positioning, messaging, and value propositions that guide regional affiliates and align with long‑term portfolio goals.
• Translate scientific and market insights into compelling strategies, launch narratives, and execution plans; effectively communicating recommendations and leading strategic discussions with global and regional stakeholders.
• Develop and refine global brand plans, including revenue and patient forecasts, to inform investment decisions, lifecycle strategies, and portfolio prioritization.
• Drive excellence in global launch execution: creating launch frameworks, ensuring best practices are shared across affiliates, and monitoring progress to anticipate and resolve challenges.
• Identify and manage external agencies, vendors, and partners to deliver impactful global campaigns, educational initiatives, and engagement platforms.
• Serve as a trusted resource to executive leadership in identifying opportunities to maximize commercial value, expand indications, and differentiate in competitive markets.
• Bring innovation and new capabilities to global marketing—collaborate with IS Commercial to integrate digital, omnichannel, and data‑driven approaches to build a best‑in‑class commercial function.
• Up to 50% of travel required.

• Bachelor’s degree required (MBA preferred) with at least 15+ years of progressive commercial experience in a biotechnology and/or pharmaceutical company including strategic marketing and ideally sales.
• Proven success of developing and executing global marketing strategy.
• Experience in leading the global launch of new product in competitive spaces.
• Demonstrated ability to derive insights/analytics leading to the development of innovative marketing strategies.
• Strong leadership, with the ability to lead teams, work well cross‑functionally, and influence across the organization to create a clear sense of direction.
• Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines.
• Ability to represent Revolution Medicines well externally: strong interpersonal skills including verbal and written communication.
• Entrepreneurial mindset, with a tolerance for ambiguity, and a passion for helping cancer patients.

• Experience with an oncology launch is desired.
• Prior experience in a smaller, rapidly growing, company.
• Experience in gastrointestinal or lung cancer preferred.

Base Pay Salary Range

$256,000 — $320,000 USD

Base pay salary range is one part of…