Senior Director, Clinical Research-Program Executive-Oncology

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.

Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

Vir Biotechnology is seeking an experienced Senior Director, Clinical Research Oncology Program Executive (PE) to serve as the development team leader and single point of accountability for one or more oncology development programs. This highly visible leadership role sits at the intersection of clinical development, program strategy, and corporate execution.

The Oncology PE will be responsible for defining and driving the overall development strategy, ensuring alignment across functions, and leading cross-functional teams to achieve key development milestones. The individual will partner closely with executive leadership to shape program direction, evaluate risks and opportunities, prioritize investments, and ensure successful execution of Vir Bio’s oncology portfolio.

You will be successful in this role if you bring deep oncology drug development experience and enjoy translating complex scientific and clinical insights into clear development strategies. You are comfortable working across functions, influencing decisions at all levels of the organization, and helping teams navigate key development milestones and strategic decisions.

This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.

• Serve as the cross-functional leader and single point of accountability for one or more oncology development programs
• Define and drive overall program vision, clinical development strategy, key milestones, and integrated development plans
• Lead cross-functional program teams to align on objectives, priorities, timelines, resource needs, and risk mitigation strategies
• Partner with executive leadership and governance committees to support strategic decision-making and portfolio prioritization
• Ensure programs are appropriately resourced and provide oversight and input on major budget and investment decisions
• Leverage deep oncology and clinical development expertise to guide development strategy, clinical trial planning, data interpretation, and key program decisions
• Represent programs at senior leadership meetings, governance reviews, alliance meetings, regulatory interactions, and other external forums
• Mentor and develop team members while helping strengthen program leadership capabilities across the organization
• Own the integrated development plan and target product profile, including stage gates, evidence requirements, and clear go/no-go recommendations.
• Chair the development team, establish decision rights and accountabilities, resolve issues promptly, and elevate material tradeoffs with a recommendation.
• Ensure fit-for-purpose translational medicine, clinical pharmacology, biomarker, companion-diagnostic, and patient-selection strategies from first-in-human development through registration.
• Guide indication prioritization, sequencing, combination…