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Principal Scientist, Oncology Research

Job in San Francisco, San Francisco County, California, 94199, USA
Listing for: Gilead Sciences
Full Time position
Listed on 2026-01-01
Job specializations:
  • Research/Development
    Research Scientist
Job Description & How to Apply Below
Join to apply for the Principal Scientist, Biology role at Gilead Sciences

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead’s team plays a critical role in the discovery and development of life‑changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Responsibilities

• Mentor a lab‑based scientific team, advancing their projects and careers.

• Serve as a scientific and technical thought leader throughout the Research organization.

• Collaborate across functions to guide interdisciplinary projects, with experts in oncology, immune‑oncology, protein engineering, chemistry, translational medicine, biomarkers and clinical development. Identify project risks and mitigate effectively, while communicating with project teams and other leaders.

• Proactively ideate to accelerate early‑stage discovery activities, enhance understanding of disease mechanisms, and develop new technologies and novel targeting modalities.

• Develop expertise in relevant scientific fields and the external landscape, including the scientific literature, conference proceedings, and competitive programs. As an in‑house expert, propose creative and rigorous research to discover, validate and understand targets.

• Think critically and creatively, emphasizing nimble decision making that balances risk‑taking with thoughtful experimentation within the strategic/competitive context to fuel a differentiated pre‑clinical pipeline.

• Contribute expertise to multi‑disciplinary due diligence teams to evaluate and recommend partnerships and acquisitions.

• Contribute to research reports, INDs, and patent filings.

• Establish an external presence through peer‑reviewed publications, conference presentations, and external collaborations.

Knowledge, Experience and Skills

• Ph.D. degree and 5+ years of experience in tumor biology, drug discovery, target identification and technology development, with post‑doctoral training highly preferred.

• Strong track record of impact in scientific field, including first‑ or senior‑author publications in peer‑reviewed journals and conference presentations.

• Strong knowledge base in cancer genomics and oncogenic signaling.

• Broad technical skill set of cutting‑edge methods and models of cancer, in vitro and in vivo, with experience in biochemically analyzing protein (and protein‑nucleic acid) complexes a plus.

• Demonstrated success in leading research teams to productive, creative, data‑driven decisions.

• Team‑centric mindset, with proven managerial excellence and ability to motivate skilled team members from diverse backgrounds.

• Excellent communication and interpersonal skills.

The salary range for this position is: $ - $.

Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. Benefits include company‑sponsored medical, dental, vision, and life insurance plans.

For additional benefits information, visit

Seniority Level

Not Applicable

Employment Type

Full‑time

Job Function

Research, Analyst, and Information Technology

Industries

Biotechnology Research and Pharmaceutical Manufacturing

Apply

For current Gilead employees and contractors, please apply via the internal career opportunities portal in Workday.

Equal Employment…
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