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Senior Manager - Bioinformatics Operations

Job in San Juan Capistrano, Orange County, California, 92675, USA
Listing for: Kforce Inc
Full Time position
Listed on 2026-01-09
Job specializations:
  • IT/Tech
    IT Project Manager, IT Support, Data Security
Salary/Wage Range or Industry Benchmark: 140000 - 170000 USD Yearly USD 140000.00 170000.00 YEAR
Job Description & How to Apply Below

Senior Manager - Bioinformatics Operations

We are seeking a Senior Manager of Bioinformatics Operations to lead a regional team focused on delivering clinical‑grade bioinformatics applications that drive precision diagnostics in a fast‑paced, regulated environment.

Base pay range: $140,000 – $170,000 per year.

Key Responsibilities
  • Lead and mentor a team of 5‑7 bioinformaticians and contractors.
  • Manage daily operations of bioinformatics pipelines, ensuring service levels and turnaround targets are met.
  • Collaborate with lab operations to support sample processing and troubleshoot production issues.
  • Oversee incident response, system health monitoring, and performance metrics.
  • Drive CI/CD practices and workflow orchestration using tools like Nextflow, Snakemake, and Service Now.
  • Maintain data integrity, compliance documentation, and secure archival of clinical data.
  • Partner with engineering teams to enhance automation and implement data‑driven process controls.
  • Support software version upgrades, tech transfers, and product launches in collaboration with R&D.
  • Align with other regional managers to standardize practices and share operational insights.
  • Implement training frameworks and competency assessments to upskill team members.
Qualifications
  • 7+ years of experience ininformatics, software engineering, or related fields.
  • Strong technical background in Python, R, shell scripting, SQL, and AWS.
  • Experience with sequence aligners, variant callers, and interpretation tools.
  • Proven leadership in managing technical teams and delivering production‑grade solutions.
  • Familiarity with regulated environments (CAP, CLIA, FDA) and handling sensitive patient data.
  • Excellent communication, project management, and problem‑solving skills.
Preferred
  • MSc or PhD in Bioinformatics, Computer Science, or related discipline.
  • Agile certification and experience with international teams.
  • Experience with LIMS, variant interpretation platforms, and cloud migration.
Benefits

Comprehensive health coverage, dental, vision, HSA, FSA, 401(k) with company match, life, disability, and career development programs. Paid time off and retirement plans.

Equal Opportunity Employer. All qualified applicants will receive consideration without regard to race, color, religion, sex, gender identity, national origin, age, veteran status or disability status.

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Position Requirements
10+ Years work experience
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