Senior Director, Global Site Contracts

The Senior Director, Global Site Contracts is a strategic leadership position responsible for the global oversight, execution, and continuous improvement of clinical site contracting activities supporting sponsored clinical trials worldwide. This role provides leadership for site contract strategy, governance, operational delivery, and process optimization across all regions to ensure rapid study startup, compliant contract execution, and high-quality operational performance.

The position partners closely with Clinical Operations, Legal, Finance, Global R&D Sourcing, Compliance, CROs, and external institutions to establish and maintain scalable contracting processes, global standards, negotiation strategies, and performance metrics. The role is expected to drive operational excellence through innovative solutions, standardized methodologies, data-driven decision-making, and strong stakeholder alignment.

As a member of the Clinical Business Operations leadership team, this individual contributes to organizational strategy, workforce planning, vendor management, and functional transformation initiatives that support the evolving needs of the clinical development portfolio.

• Lead and manage the Global Contracts Management team
• Oversee activities related to the execution of clinical site contract documents and associated processes.
• Develop and enhance policies, procedures, and systems that optimize contracting operations
• Ensure compliance, quality, and efficiency across global contracting activities
• Provide training, mentorship, and supervision to the contracts team

• Develop and execute the global strategy, vision, governance framework, and operating model for Clinical Site Contracts, ensuring alignment with Global Clinical Operations (GCO) objectives and portfolio priorities

• Serve as a member of the Clinical Business Operations Leadership Team, contributing to functional strategy, organizational planning, risk management, and operational excellence initiatives

• Develop and oversee global governance models, portfolio plans, project plans, and operational frameworks that support efficient and compliant clinical site contracting activities

• Determine, implement, and continuously evolve global policies, procedures, SOPs, templates, playbooks, and best practices for site contract management

• Identify and maintain a globally consistent contract negotiation model that balances speed, compliance, quality, and business needs across regions

• Provide global oversight and accountability for the management of all clinical contract agreements, including but not limited to:

• Clinical Trial Agreements (CTAs)

• Investigator Agreements

• Confidential Disclosure Agreements (CDAs)

• Site Master Service Agreements (MSAs)

• Pharmacy Agreements

• Ancillary Agreements

• Consulting Agreements

• Subcontractor Agreements

• Other agreements supporting the clinical trial lifecycle.

• Ensure timely development, negotiation, execution, amendment, maintenance, and close-out of global site contracts in support of study startup and study conduct milestones

• Serve as the senior escalation point for complex contractual negotiations, site-specific issues, and institutional contracting challenges

• Directly participate in high-priority or complex site negotiations when required

• Maintain oversight of contract quality, compliance, and execution consistency across all regions and programs

• Partner with Clinical Operations, CROs, and study teams to identify country-, site, and study-specific contracting risks that could impact startup timelines, enrollment, or study execution

• Develop and implement proactive risk mitigation strategies to accelerate study startup and reduce contracting delays

• Conduct regular risk reviews against study and portfolio milestones, identifying and escalating potential risks to timelines and deliverables

• Leverage contracting intelligence, market insights, and operational metrics to support study feasibility, planning, and startup execution

• Provide strategic oversight and guidance on study startup activities and contracting dependencies across the portfolio

• Collaborate closely with Clinical Operations, Legal, Compliance, Finance, Tax, Procurement, Clinical Outsourcing, and Development stakeholders to ensure successful execution of clinical trial contracting…