Sr. Manager​/Associate Director, Quantitative Science

Sr. Manager/Associate Director, Quantitative Science

Join the Sr. Manager/Associate Director, Quantitative Science role at Bio Marin.

Bio Marin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health.

From research and discovery to post‑market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first‑in‑class and best‑in‑class therapeutics that provide meaningful advances to patients who live with genetic diseases.

The Quantitative Science team at Bio Marin performs statistics and data science across research and development and beyond. As the Senior Manager or Associate Director of Quantitative Science, you will assume the role of a statistician/data scientist and play a pivotal role in supporting different functional areas. This influential and self‑sufficient position will make significant contributions to drug discovery, nonclinical research, preclinical research, experimental medicine, biomarker development, clinical development, post‑approval/medical areas, real‑world data/real‑world evidence (RWD/RWE), genomics, business development, and manufacturing.

Your primary responsibility will be to ensure excellence in the design, analysis, interpretation, and communication of data. Additionally, you will actively engage with counterparts to foster collaboration and champion the use of quantitative thinking.

• Broad subject matter expertise in statistics and data science with hands‑on experience in application in diverse areas
• Proficiency in statistics, advanced data science, and programming
• Ability to develop fit‑for‑purpose statistical methodologies and software tools is a plus
• Exceptional communication and interpersonal skills

• Perform statistical experimental design, analysis, interpretation, and reporting, including:
  • Estimate sample size and aid in study design including conducting simulations
  • Conceptualize solutions to unique challenges and develop analysis methods and analysis programs accordingly
  • Explore and develop the use of artificial intelligence (AI) and machine learning (ML)
  • Write statistical analysis reports and give presentations
• Develop statistical applications that enable researchers to analyze repetitive experiments
• Conduct outreach to internal functions, establishing collaborations and providing education to identify opportunities to apply statistics and data science that positively impact the business
• Provide guidance and direction to junior staff on the team

• M.S. in Biostatistics, Statistics, Data Science, or a similar field required.
• Ph.D. in Biostatistics, Statistics, Data Science, or a similar field preferred.
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Minimum qualifications:

5 years of experience in the pharmaceutical and/or biotech industry for Ph.D. candidates or 7 years for Master’s candidates for associate director; 2 years for Ph.D. candidates or 4 years for Master’s candidates for senior manager.

• Basic broad knowledge of the research, development, and associated areas in the pharmaceutical/biotechnology field
• Broad knowledge of statistical methods and ability to solve problems creatively and pragmatically
• Scientific curiosity and ability to learn
• Exceptional consultative, conversational, written communication, presenting, collaborative, teaching, and interpersonal skills
• Adaptability and ability to thrive in a dynamic, diverse, and matrixed environment

• Hands‑on knowledge of statistical methods applicable across research and development such as time‑to‑event analyses, analysis of covariance, mixed models for repeated measures, categorical data approaches, Bayesian methods, simulation approaches, AI and ML, graphical methods, etc.
• Hands‑on knowledge of study design and sample size calculation
• Strong programming skills in at least two of SAS, R, or Python

• Proficiency in or demonstrated ability to learn developing specifications…