US Medical Senior Director, Medical Affairs Evidence Generation

US Medical Senior Director, Medical Affairs Evidence Generation

Location:

Santa Monica, CA (preferred) or Foster City, CA

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR‑T cell therapies have changed the paradigm. But we're not finished yet.

Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.

As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations.

• Serve as a senior member of the Evidence Generation (EG) leadership team, co‑driving the evolution of Kite’s US evidence generation strategy and value proposition.
• Support the development and execution of the Integrated Evidence Plan (IEP) in collaboration with the Evidence Generation Function, Global Medical Affairs Strategy, and Product Teams.
• Identify critical evidence gaps and define the most appropriate research approaches (retrospective, prospective, interventional, RWE) to address unmet needs.

• Provide scientific and medical oversight for all Medical Affairs / Kite‑Sponsored Studies, including interventional trials, non‑interventional studies, and US Strategic Alliances.
• Lead the development of clinical study concepts and protocols in collaboration with Medical and Clinical Development teams.
• Oversee the US Investigator‑Sponsored Research (ISR) and Collaborative Research (CR) program, ensuring scientific merit, alignment with strategic priorities, and compliance.
• Serve as the Medical Monitor for assigned evidence generation studies, ensuring timely execution, data quality, and compliance with GCP and internal SOPs.
• Provide strategic oversight and clinical guidance to operational teams for timely and impactful execution.

• Lead the medical review, interpretation, and communication of study results, including drafting publications, abstracts, posters, and internal/external presentations.
• Serve as a medical expert for study data, engaging with internal and external stakeholders and Key Opinion Leaders (KOLs).
• Collaborate with Global Medical Strategy to ensure accurate and compliant dissemination of generated evidence.

• Partner across Kite Medical Affairs, Clinical Development, Translational Medicine, Regulatory Affairs, and Product Teams to build integrated cross‑functional capabilities.
• Mentor and provide guidance on evidence generation best practices, methodologies, and compliance requirements.
• Ensure all evidence generation activities comply with Kite/Gilead policies, local regulations, and the highest ethical standards.
• Design and implement strategies to accelerate evidence generation through external platforms, technologies, and data‑driven insights.
• Represent the Evidence Generation function at core Kite governance bodies (e.g., Product Teams, Global Medical Teams, JSC).

• Champion medical innovation by integrating emerging scientific trends and technologies into US evidence generation strategies.
• Lead external engagement efforts to enhance scientific credibility and foster meaningful partnerships with healthcare professionals and institutions.
• Serve as a member of the central External Research Program screening/review committee and manage joint steering committees for strategic collaborations.

Required

• MD or equivalent medical degree.
• Minimum 5 years of experience in the biopharmaceutical industry, with at least 5 years in medical affairs, clinical development, or evidence generation.
• Proven leadership in designing and managing clinical trials, including Phase IV and investigator‑sponsored studies.
• Understanding of the cell‑therapy landscape, including regulatory and post‑approval evidence needs.

Preferred

• Experience in CAR‑T or related…