Principal Engineer, Assay and Data Automation

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:

Cell Therapy Analytical Development (CTAD) is seeking a highly skilled and experienced Principal Engineer to join the Assay and Data Automation team. This role will lead the design, development, and implementation of state-of-the-art automation solutions for a variety of analytical methods and technologies supporting cell therapy programs.

The Principal Engineer brings hands‑on expertise in assay automation and possesses a strong technical background in automation design, development, and deployment within both GMP and non‑GMP labs. This individual will foster effective partnerships and collaborate cross-functionally with internal and external stakeholders—including CTAD functions and CTDO departments—to build analytical automation solutions to enhance sample throughput and capacity while reducing hands‑on time, time‑to‑result, repetitive strain, and assay variability.

• Independently design, develop and implement partial and integrated automation platforms for bio‑analytical methods that are performed in GMP and non‑GMP labs.
• Effectively communicate experimental results to influence program decisions and support regulatory filing strategies.
• Partner with external integration vendors to establish end‑to‑end integrated analytical automation platforms.
• Collaborate with stakeholders to ensure automation designs and development meet the business goals and needs.
• Support all functions related to automation technical transfer into GMP lab, including documentation associated with requirements gathering, development, IQ, OQ, and method validation.
• Optimize automated systems, expand capabilities, and support technical investigations.
• Lead automated method qualification and operator training activities.
• Work with automation team members to support or maintain automated systems as needed.
• Develop and maintain documentation related to automated analytical methods and technologies.
• Provide technical support to end‑users and stakeholders.
• Train and mentor other team members on automation technologies.
• Collaborate effectively across functional groups.

• BS or MS in engineering discipline with 8+ years of integrated automation experience.
• Demonstrated experience as an automation developer in automated liquid handlers associated software (e.g. Hamilton and Venus software), end‑to‑end assay automation workflows, and integrated automation systems.
• Proven track record in developing and implementing automated laboratory workflows and high‑throughput methods within the biotechnology or pharmaceutical industry, including systems configuration, liquid handling, and method programming.
• Experience designing, programming, operating, and troubleshooting end‑to‑end integrated automation systems including lab orchestration scheduler software (e.g. High Res Bio Solutions systems and Cellario platform).
• Ability to identify/understand sophisticated customer needs and develop automated solutions for laboratory workflows.
• Experience leading evaluation and implementation of new and novel technologies.
• Experience migrating bench techniques to hands‑free automated systems is required.
• Excellent problem‑solving skills.
• Strong interpersonal skills with the ability to develop and maintain effective professional relations across…