Research Technician

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states.

Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Paulovich Lab at Fred Hutch ((Use the "Apply for this Job" box below).) is an interdisciplinary team whose mission is to develop and implement tools for protein quantification to enable precision medicine via patient selection and characterization of novel therapeutic targets. The lab has a major focus on mass spectrometry (MS)-based proteomics (both untargeted and targeted), as well as integrating proteomic data with genomic data. Our group is highly collaborative, participating in national and international consortia in which teams of scientists, statisticians, and clinicians work together to solve clinical or biological problems to impact human health.

This is a terrific opportunity within the Paulovich lab for a highly motivated and entry level full-time Research Technician to join our translational proteomics team to help drive translational projects forward towards clinical applications by performing bench-level experiments in support of proteomic, genomic, and transcriptomic analyses of clinical and preclinical biospecimens. The ideal candidate will be able to work as part of a team as well as independently to follow established standard operating protocols (SOP) in a CLIA/CAP laboratory environment.

• Work with antibodies (immunoaffinity purification, immobilization on solid supports, ELISAs)
• Perform expansion of mammalian cell lines in culture
• Process proteomic samples for LC-MS analysis (e.g., protein extraction, fractionation, immuno-depletion, trypsin digestion, alkylation, reduction, etc.)
• Perform biochemistry/protein chemistry techniques (SDS-PAGE, protein quantification assays, ELISA)
• Follow standard operating protocols (SOP) in a CLIA/CAP laboratory environment including participating in annual competency and proficiency testing
• Collaborate effectively with an interdisciplinary team spanning expertise in medicine, biology, analytical chemistry, and statistics
• Maintain laboratory equipment, records, research results files, and databases
• Assist with written progress reports and development of standard operating protocols (SOPs)
• Assist with writing and co-authoring scientific manuscripts (in peer-reviewed journals)
• Work comfortably in a milestone-driven environment, with quarterly objectives
• Perform other duties as required

MINIMUM QUALIFICATIONS:

• Bachelor's degree in a related scientific field or equivalent combination of education and experience
• Demonstrated scientific knowledge in the area of study
• Demonstrated basic laboratory skills

PREFERRED QUALIFICATIONS:

• Previous independent experience in a laboratory bench setting in Protein Chemistry, Analytical Chemistry, Clinical Chemistry, Biochemistry , Molecular Biology or related discipline, separate from college level study.
• Exquisite attention to detail and…