Research Associate; RNA Biology

Research Associate (RNA Biology)

• Posting date: 12 February 2026
• Hours:
  
  Full time
• Closing date: 26 February 2026
• Location:
  
  Sheffield, S10 2TN
• Company:
  University of Sheffield
• Job type:
  Temporary
• Job reference:

Do you have a passion for RNA, gene‑regulation and development? The Sudbery, Barbaric and Wilson laboratories in the School of Biosciences at the University of Sheffield wish to recruit a postdoctoral researcher to work on a Leverhulme funded project analysing how splicing in the 3' UTR of genes can regulate their developmental dynamics. The project will involve using both the latest molecular and computational techniques to investigate how splicing might affect RNA stability dynamics across development.

You will use CRISPR engineered cell lines carrying degron tags for key proteins to dissect the molecular mechanisms in this process. You will use second and third generation DNA sequencing technologies and other molecular and cell biology approaches in the project. You will develop new bioinformatic pipelines to analyse the results of these experiments, as well as making the analytic approaches available to the community.

You will conduct experiments using molecular biology techniques, including PCR and cloning; generate CRISPR engineered cell lines; perform high-throughput sequencing; analyse sequencing data with custom pipelines; collaborate with interdisciplinary teams; and publish findings.

You will have a PhD (or be close to completion/have equivalent postdoctoral level work experience) in Biochemistry, Genetics or Molecular biology along with proven knowledge of, and a track record of research in UTR biology and RNA stability, experience of standard Molecular Biology experimental techniques such as PCR and molecular cloning, and experience with analysing data from high-throughput sequencing experiments, including analytic pipelines, and the development of novel statistical analyses.

You will demonstrate a collaborative mindset, a willingness to acquire new skills, and enjoy working in an interdisciplinary way. You will be part of a community of researchers working towards common or related goals and fostering such a community.

We offer a fantastic range of benefits including a highly competitive annual leave entitlement (with the ability to purchase more), a generous pension scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more. Find out more at

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