Sr. Director, Supply Chain Operations Somerville, Massachusetts

Position: Sr. Director, Supply Chain Operations Somerville, Massachusetts, United States
Somerville, Massachusetts, United States

About Genetix Biotherapeutics

At Genetix Biotherapeutics every role has meaning, every team member is respected, and every day is a chance to make a difference. When you join Genetix, you become part of a company pursuing curative gene therapies to give patients and their families more days. We are doers, thinkers and collaborators who embrace and live by our values.

Our innovation is rooted in the diversity of our teams and results are achieved through cooperation and the integration of multiple viewpoints. We approach every challenge with radical care.

Senior Director, Supply Chain Operations

This individual will oversee all aspects of supply planning, materials management, logistics, and distribution to ensure reliable supply of commercial products in compliance with global regulatory and quality standards. The ideal candidate will bring deep experience in advanced therapy manufacturing, vendor management, and cross‑functional collaboration across Manufacturing, CMC, Quality, Regulatory, and Finance.

Responsibilities

Strategic Leadership

• Develop and execute the global supply chain strategy aligned with corporate goals and product lifecycle with an emphasis on expanding capacity and secondary sourcing

• Build and lead a high‑performing supply chain organization, including planning, sourcing, logistics, and systems

• Demonstrated leadership across multiple functions in Technical Operations to bridge gaps between Manufacturing, Supply Chain Operations and Patient Supply Teams

• Drive identification, contracting, relationship management, and performance of critical GMP supply chain partners including leading RFI/RFPs for new vendors

• Oversee raw material suppliers, logistics providers, and starting material partners to ensure performance and compliance through implementation of Supplier Management Program

• Directly partner with Manufacturing, CMC, and Quality teams for management of External Manufacturing Partners

Planning and Operations

• Lead Sales & Operations Planning (S&OP) to ensure optimal alignment of supply and demand across all commercial programs

• Manage global inventory and materials planning to support manufacturing schedules and mitigate supply risks by working closely with external manufacturing organizations

• Oversee the forecasting, production scheduling, and capacity planning processes in collaboration with Manufacturing, Quality and Patient Supply teams

Logistics and Distribution

• Lead global logistics operations, including cold chain management, product distribution, and import/export compliance across the Technical Operations business

• Work with vendors to achieve cost savings across the supply chain in line with COGM reduction initiatives

• Partner directly with the Patient Supply Team to harmonize logistics and operations across the business

• Lead labeling, artwork and packaging initiatives in collaboration with Commercial teams

Systems and Analytics

• Oversee implementation and optimization of ERP/MRP systems to improve visibility, data accuracy, and decision‑making

• Use analytics and KPIs to monitor performance, identify risks, and drive proactive action plans

Qualifications

Education and Experience

• Bachelor’s degree in Supply Chain, Engineering, Life Sciences, or related field; advanced degree (MBA or MS) preferred

• 17+ years of progressive experience in supply chain management and manufacturing with at least 8 years in leadership roles within the biotechnology, pharmaceutical, or life sciences industry

• Proven experience managing supply chain operations in commercial cell & gene therapies

• Experience leading LVV manufacturing and supply planning

• Preferable experience leading Manufacturing or MS&T functions in previous roles

Skills and Competencies

• Strong understanding of global supply chain best practices, including S&OP, inventory optimization, and supplier management

• Deep knowledge of cGMP, GDP, and regulatory requirements (FDA, EMA, ICH)

• Exceptional leadership, communication, and cross‑functional collaboration skills

• Experience scaling supply chain organizations during rapid growth and scaling

• Proficiency with ERP systems (e.g.,…