Research Scientist, Inflammatory Bowel Disease; IBD) Drug Discovery

Position: Research Scientist, Inflammatory Bowel Disease (IBD) Drug Discovery
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Job Description Objective /

Purpose:

The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a Research Scientist to join our biology and cross-functional discovery teams and create novel drug candidates.

Your role :provides technical leadership for research project implementation and coordination,begins at the conception of new projects and helps advance to candidate selection,generates exciting and rigorous data that drive confident decisions,contributes critical thinking, technical expertise, and scientific insight to teamwork, and maintains our Takeda culture that promotes creativity, open communication, cooperation, and urgency while delivering the highest quality of science for drug discovery.

Accountabilities:

Identify, plan, and execute well-defined scientific projects

Initiate investigation of new experimental approaches to specific problems using scientific theory and technical literature

Use defined practices and theoretical knowledge to perform analyses, interpret results, and determine appropriate actions

Utilize relevant information, technology, and resources to proactively contribute to solving complex problems and achieving objectives as a team Prepare and present comprehensive project and technical reports to a range of internal and external audiences

Education & Competencies (Technical and Behavioral):
PhD degree in a scientific discipline (or equivalent), or MS with 6+ years relevant experience, or BS with 8+ years relevant experience

Demonstrated accomplishments in inflammation and/or immunology research, with a track record of applying scientific insight to address complex biological questions; experience in inflammatory bowel disease is a plus Strong expertise in molecular biology, cell biology, and immunology, with experience developing cell-based and biochemical assays

Hands-on experience with key technologies including flow cytometry, primary human immune cell and fibroblast culture, cytokine analysis (AlphaLISA, MSD, ELISA), qPCR, and gene editing approaches (e.g., CRISPR, siRNA)
Experience developing in vitro assays to characterize small and large molecules for potency and mechanism of action

Experience contributing to the design and execution of in vivo efficacy, pharmacology, and MoA studies in rodent models

Ability to independently design and execute experiments while contributing effectively within a collaborative, matrixed team environment

Strong problem-solving skills with the ability to generate high-quality data and derive insights that inform project decisions

Excellent written and verbal communication skills and the ability to work effectively in a highly matrixed environment

Strong organizational and multi-tasking skills with attention to detail

Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For

Location:

USA - MA
- Cambridge
- Binney StU.S. Base Salary Range:$ - $The estimated salary range reflects an anticipated range for this position. The actual base salary offered may…