Associate Scientist, HTS & NGS

Reference: 631939

Posted:

Location:

Cambridge, Massachusetts Company:
Planet Pharma Group Contact:
Applications Email: applications

Location:

Cambridge, MA – Onsite

Position Summary:

biotech client is seeking a highly motivated contract Associate Scientist to join our HTS-NGS operations team and work with an enthusiastic team of highly skilled scientists. The ideal candidate for this lab-based position is committed to delivering high quality results in a timely manner. This is an exciting opportunity to be part of a collaborative team and contribute to the development of next-generation RNA editing technology and therapeutics in a fast-paced biotech company.?

Key Responsibilities:

Independently design and execute high-throughput cell-based assays to support oligonucleotide platform and portfolio projects  Perform amplicon-seq library preparation and quality control, operate and maintain NGS platforms and associated laboratory equipment ?

Troubleshoot HTS assays, library preparation, and sequencing workflows as needed Analyze and present HTS-NGS data based on results in a team setting; collaborate with cross-functional teams to support lead discovery Support NGS scientists in operational tasks, including inventory management, assay development, and operations improvement Accurately document project and sample information, protocols, and experimental details through an Electronic Lab Notebook (ELN)

Required Qualifications:

MS with 3+ years or BS with 5+ years of experience in molecular biology, cell biology, or related field 1+ years of hands-on experience with high-throughput assays and automated workflows

Experience with cell culture techniques, including plating and transfection in 96/384-well formats

Experience with NGS assays: amplicon-seq and RNA-seq, including primer design, library preparation, quantification, and data quality control Demonstrated expertise in molecular biology techniques: RNA/DNA isolation, transfection, PCR/qPCR, gel electrophoresis

Familiarity with liquid handling systems (e.g., Viaflo
96/384, HiRes/Certus Flex, Tempest) is highly preferred  Hands-on experience with next-generation sequencing platforms and equipment including Illumina (MiSeq i100), Qubit, Tape Station, and Fragment Analyzer is highly preferred ?

Experience with LIMS systems (Benchling) and project management tools (Jira/Confluence)?? ?

Strong troubleshooting skills and ability to suggest and implement new solutions independently Excellent written and verbal communication skills with attention to detail Ability to thrive in a fast-paced and evolving environment