Principal Mechanical Engineer Project Manager

Principal Mechanical Engineer Project Manager

Genentech is establishing a new Campus Development Team (CDT) to oversee the implementation of the Campus Vision Plan (CVP) for the South San Francisco campus. This Senior Principal Mechanical Engineer position provides single‑point accountability for the successful end‑to‑end delivery of all mechanical systems within the gRED development, with a primary focus on the complex laboratory and research environments. The role also provides expertise for the supporting Vivarium, Utility Plant, and Electrical Distribution Hub as part of the CVP.

• Provide technical leadership and deep subject‑matter expertise for the mechanical design of gRED research laboratories, specialized vivarium spaces, and associated projects.
• Lead design and planning of HVAC, plumbing, fire protection, building controls, automation, and energy management critical to laboratory operations and specialized vivarium environments.
• Coordinate with Utility Master Plans to ensure upgrades to critical mechanical infrastructure support reliability, redundancy, and scalability required by new lab facilities.
• Serve as a respected industry expert on laboratory mechanical design, engaging with the Roche/Genentech internal and industry external network to learn, influence, and collaborate on new technologies and best practices for gRED.
• Ensure scientific user requirements are incorporated into robust technical solutions for the gRED project.
• Provide expert design guidance on HVAC, plumbing, fire protection, building controls, automation, and energy management, offering strategies for flexible 'plug‑and‑play' capabilities and robust backup systems to protect critical experiments, data, and animal life‑support systems.
• Work closely with other technical leads to ensure seamless integration of mechanical systems with lab‑specific platforms such as Building Automation Systems (BAS) and environmental monitoring systems.
• Serve as the mechanical SME in all design and user‑group meetings, providing clear technical options analysis and advocating for designs that prioritize scientific workflow, flexibility, and safety.
• Ensure all mechanical designs align with Roche/Genentech and site‑specific standards, focusing on laboratory design and vivarium operations standards.
• Coordinate mechanical scope into a comprehensive strategy to address technical needs across all aspects of the gRED project, from main infrastructure to point‑of‑use in the lab.
• Support broad Design Engineering & Construction Services process improvement projects and LEAN initiatives, applying these principles to improve lab design and delivery.
• Drive innovation in mechanical systems for R&D environments, adopting technologies that improve lab flexibility, energy efficiency, and operational reliability.
• Contribute to the project‑wide mechanical infrastructure strategy, ensuring new gRED labs are adaptable for future scientific platforms and technologies, reducing total cost of ownership while maximizing uptime and research continuity.
• Engage in continuous learning and professional development through the Roche engineering network and industry organizations such as ASHRAE and ISPE.

• Project planning and coordination: develop and maintain a comprehensive project plan, coordinate with architects, engineers, and contractors, identify and mitigate risks, and report progress to senior management.
• Budgeting and resource management: support the development and management of the project budget, ensuring cost control and effective resource allocation, and oversee procurement activities.
• Stakeholder management: build and maintain strong relationships with internal and external stakeholders, fostering collaboration and alignment.
• Team leadership: clarify roles, foster a collaborative work environment, mentor team members, and contribute strategic design expertise.
• Quality control: implement and enforce strict quality control measures to ensure compliance with industry standards and specifications.

• Bachelor’s degree in Mechanical Engineering or equivalent.
• 15+ years of pharmaceutical technology experience in industry or academia after…