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Portfolio Leader

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Genentech
Full Time position
Listed on 2026-10-19
Job specializations:
  • Finance & Banking
    Portfolio & Asset Management, Data Scientist
Salary/Wage Range or Industry Benchmark: 149300 - 277300 USD Yearly USD 149300.00 277300.00 YEAR
Job Description & How to Apply Below
The Position

At Roche/Genentech, we have a bold Pharma Ambition to deliver 20 transformative medicines addressing diseases with the highest societal burden by 2030. With this vision top of mind, our purpose is to co-create and deliver the target portfolio for the benefit of patients.

We want you to join our vision and be part of our passionate, collaborative, global Portfolio Strategy & Management (PSM) community!

We are a strong, close, trusting community that lives new ways of working and operates from a creative mentality. We are THE place for talent to grow and contribute; our talent feels valued, connected, and a sense of belonging to something impactful. We have high impact; customers draw on our expertise to help them deliver the target portfolio more effectively/efficiently. We stop lower-value work.

We’re BOLD. We try things, openly discuss and learn from mistakes and failure, experiment and iterate to achieve our aspirations.

The Opportunity:

As Portfolio Leader you will focus on providing Portfolio Strategy, Portfolio Management and Portfolio Insights & Analytics to partners across Pharma and the Roche enterprise. You will be expected to closely collaborate with colleagues in relevant groups beyond PSM in co-creating deliverables. You will also be involved in the development and application of analytical tools, financial models, and data-driven insights to shape the Pharma portfolio.

Key accountabilities for team members include, but are not limited to, a combination of the following areas:

  • Strategic investment analysis
    - Provide analytical expertise to evaluate strategic options, leveraging financial modeling (rNPV, scenario analysis, trade-off optimization) to quantify risk, asset value, and competitive positioning that guide capital allocation decisions.
  • Strategy support
    - Partner with Pharma Leaders to co-create and deliver robust portfolio and business strategies that provide the scaffolding for Pharma portfolio decisions
  • Portfolio assessments and presentations
    - Manage and communicate portfolio dynamics (risk, value, mix, competitive positioning etc.) to inform portfolio decisions and strategy updates. Develop portfolio content and actionable insights presented to Executive Leadership.
  • Decision support and valuation
    - Active thought partner to teams and decision-makers including, defining/scoping of tactics to deliver on defined business strategies
  • Decision management and ecosystem architecture
    - Ensure decision quality by architecting the path to a decision, the decision making model, and portfolio prioritization. Design/evolve advice seeking and fit-for-purpose engagement opportunities, and develop/evolve resources and guidance to support decision making and portfolio management.
  • Insights & analytics
    - Design, develop and improve portfolio metrics, analytics, and dynamic visualizations that enable operational efficiency and optimal decision-making and targeted communications. In addition, provide and update guidance on valuation and risk methodologies used by teams and decision-makers. Key deliverables include quarterly Pharma Portfolio Reports, annual R&D performance benchmarking, business planning and ad hoc requests.
Who You Are
  • Bachelor's degree in Biostatistics, Applied Mathematics, Finance, Data Science, Engineering, or a similar quantitative discipline;
    Advanced degree (MS, PhD, MBA) highly preferred
  • Strong understanding of disease/drug development to translate competitive/industry insights into actions.
  • You have strong experience using a combination of quantitative rigor and collaborative partnership across matrixed technical teams (including Finance, Data Science, and Informatics) to ensure strategic models are translated into actionable portfolio delivery.
  • You apply…
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