Executive Director, Head of U.S. Medical Population Science & Health

The Opportunity

The Head of US Medical Population Science & Health (USM PS&H) will lead the CMG US Medical Population Science & Health team reporting to the VP Head of US Medical. This role is part of the US Medical Leadership Team, alongside other senior leaders such as the VP, Head of Scientific Operations. This individual will manage a team of two Medical Science Health Population Directors, and one Field Medical Health Population Director, focused on advancing population science and health outcomes for all Genentech and Roche patients and aligned with specific therapy area initiatives.

They will ensure long-term, sustainable above-brand PS&H strategies that support Roche’s 2030 vision.

The Head of USM PS&H will collaborate with other USM teams and functional leads to ensure enterprise-wide strategic alignment, acting as a key medical spokesperson internally and externally with various committees, regulatory bodies, and industry forums. This individual will represent USM across the enterprise, engaging with executive teams from PD, gRED, pRED, and CMG, serving on the USLT and ecosystem leadership teams, and maintaining global alignment.

Externally, they will be the primary USMA PS&H contact for C-suite healthcare professionals, while their team will focus on engagements with the Field and Medical Network.

• Strategic Leadership & Vision

  • Build sustainable Population Science & Health (PS&H) strategies aligned with CMG and Roche 2030 visions, ensuring alignment with Squads and Medical teams. Integrate PS&H into USM strategy and field medical execution through playbooks, frameworks, and training.

  • Embed Population Science and Health across the Medical organization, leading strategy and efforts, and translating enterprise vision into cross-portfolio clinical and evidence generation plans. Lead interactions with regulatory agencies and experts, partnering with Squads to develop and communicate integrated PS&H strategies.

• Operational & Financial Accountability

  • Responsible for budget management of PS&H activities in USMA, delivering Phase IIIb/IV studies, and strengthening Genentech s ability to execute clinical trials, especially for specific populations, to reduce trial delays or non-approvals.

  • Drives evidence generation and trial outcomes by providing U.S.
    
    -specific data for regulatory approvals, payer negotiations, and inclusive research standards, aiming for faster clinical trial enrollment and increased participation from underrepresented communities; may also serve as Medical Monitor back-up and embed best practices for broader patient representation in trials.

• Cross-Enterprise Representation & Collaboration

  • Represent USMA PS&H internally, interfacing with executive leadership teams (PD, gRED, pRED, CMG), and externally, representing USMA PS&H at USM and PH CoE leadership meetings. Proactively guide Field Medical and USM engagement with underserved health systems and clinicians to expedite recruitment and successful completion of critical Phase IV trials. Lead across the One Roche Enterprise, engaging with C-Suite Executives from Foundation Medicine, Flatiron, and Roche Diagnostics.

• Field Population Health Support Oversight

  • Provide strategic direction and guidance for the Medical Science Health Population Directors and Field Medical Health Population Director, ensuring alignment with national objectives and equitable health outcomes by strengthening partnerships with underserved health systems, community providers, and ecosystem stakeholders, and equipping field medical teams to communicate PS&H value, build trust, strengthen trial site relationships, and support patient enrollment, while also ensuring consistent bi-directional knowledge flow between field team insights and internal strategy to optimize PS&H impact and responsiveness.

• Compliance, Risk & Governance

  • Ensure the PSH team follows compliance governance practices and processes relevant to collaborative work (e.g., confidentiality, intellectual property, data privacy, interactions with customers, pharmacovigilance) and proactively manage risk in external collaborations and evidence generation, ensuring alignment with Roche…