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Human Resources Manager

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: GenEdit
Full Time position
Listed on 2026-01-12
Job specializations:
  • HR/Recruitment
    Employee Relations, Talent Manager, HR Manager, Regulatory Compliance Specialist
Salary/Wage Range or Industry Benchmark: 60000 - 80000 USD Yearly USD 60000.00 80000.00 YEAR
Job Description & How to Apply Below

Gen Edit is a rapidly-growing, early-stage company pioneering a proprietary delivery platform with the potential to transform genetic medicine. Our interdisciplinary team collaborates across chemistry, payload, formulation, screening, and preclinical development to drive the next generation of gene therapies. We foster an exciting, dynamic work environment and are expanding across all functions. Join us at our Brisbane, CA headquarters to shape the future of genetic medicine.

Position

Summary

Gen Edit is seeking a full-time HR Manager who will manage day-to-day HR operations and support key HR initiatives. This role is highly operational and hands‑on, responsible for ensuring the smooth execution of HR processes including recruitment, onboarding, payroll administration, employee relations, compliance, and HR documentation. The HR Manager will work closely with leadership and employees to foster a positive, compliant, and efficient workplace.

Key Responsibilities
  • HR Operations: Manage and execute daily HR operations including employee record maintenance, HR documentation, onboarding, offboarding, and HR policy administration.
  • Talent Acquisition Support: Assist hiring managers in coordinating recruitment efforts, posting job advertisements, scheduling interviews, participating in phone screenings, and managing candidate communication.
  • Payroll Administration: Oversee bi‑weekly payroll processing using Gusto (or similar platform), ensuring accuracy and timeliness in collaboration with Finance and external vendors.
  • Compliance and Reporting: Ensure compliance with federal, state, and local labor laws; maintain up‑to‑date employee files; and assist in preparing compliance documentation and audit responses.
  • Employee Relations Support: Serve as an initial point of contact for employee inquiries and concerns; support conflict resolution processes and assist managers with employee performance issues when needed.
  • Benefits Administration: Coordinate open enrollment, benefit communications, and liaise with benefits providers to resolve employee issues.
  • HR Process Improvement: Recommend and help implement improvements to HR systems, documentation, and workflows to enhance operational efficiency as the company grows.
Qualifications & Education
  • Bachelor’s degree in Human Resources, Business Administration, or a related field required.
  • 4–7 years of hands‑on HR experience in a fast‑paced environment, preferably in biotech, tech, or startup settings.
  • Experience across multiple HR functions including recruiting, onboarding, payroll, compliance, and employee support.
Skills
  • Solid understanding of U.S. labor laws and HR best practices.
  • Proficiency in HRIS/payroll systems (Gusto preferred).
  • Excellent organizational, communication, and problem‑solving skills.
  • Ability to manage multiple tasks while maintaining high attention to detail.
Preferred Qualifications
  • Bilingual in Korean and English.
  • Previous experience supporting a hybrid or global workforce is a plus.

There is a new universe of possibilities for effective and safe genetic medicines. Gen Edit was founded to realize this full potential – overcoming current limitations in genetic medicine delivery to cure a broad range of diseases and make a profound difference in peoples’ lives.

Seniority level:
Mid‑Senior level

Employment type:

Full‑time

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