Senior Research Associate II – Vivarium Operation T--PCP

WHO WE ARE

Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We seek a talented and experienced Senior Director, Corporate Controller to work hybrid based in our South San Francisco office.

Arsenal Bio’s mission and purpose are very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.

Driven by a collective of diverse experts across multi-scientific disciplines and clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.

This means you’ll have the opportunity to work with the best talent in the field of cell therapy and be part of ONE TEAM, which advances therapies for patients who need it most.

We are seeking a highly motivated Vivarium Operation Research Associate (Contract) to support the evaluation of programmable cell therapies. The ideal candidate will be responsible for hands‑on execution of oncology animal models, strictly adhering to IACUC guidelines for animal welfare. Key responsibilities include animal handling, compound administration (various routes), tumor burden quantification (volumetric and bioluminescence imaging), and sample collection/processing. The associate will also be expected to maintain meticulous experimental records, and support general vivarium and laboratory operations, including equipment maintenance and cross‑functional task coordination.

Candidates with experience in cell culture and flow cytometry are preferred.

• Conduct oncology animal models for evaluating programmable cell therapy
• Adhere to IACUC guidelines to ensure ethical treatment and welfare of laboratory animals
• Support the Vivarium Operations and In Vivo Translation teams by conducting animal model studies in oncology to evaluate the activity of programmable cell therapy
• Maintain and expand cancer and therapeutic cell lines
• Execute hands‑on responsibilities including, but not limited to animal handling and restraint, administration via various routes, in‑life measurements, clinical observations, sample collection and processing, and accurate data collection
• Introduce and quantify tumor burden by volumetric measurement and bioluminescent imaging
• Harvest and analyze in vivo samples by flow cytometry and other in vitro assays
• Document, organize, maintain, review, and report experimental records for research and regulatory requirements
• Support vivarium and laboratory operations
• Manage, maintain, and purchase laboratory equipment and consumables
• Communicate and coordinate daily tasks cross functionally with internal and external partners

• Bachelor's degree with 4+ years of relevant experience or Master’s degree in oncology, immunology, biotechnology, or a related field with 2+ years of relevant industry or academic experience
• Cell culture experience with mammalian cell lines with additional weight given for CAR‑T cells
• Animal health experience in identifying clinical observations and providing treatments
• Extensive experience in establishing mouse tumor models in immune competent and compromised animals
• Proficiency in drug administration (SQ, IP, IV, and PO)
• Proficiency in various blood collection routes (Sub‑M and others)
• Proficiency in rodent full body necropsy
• Software experience in Excel, Google suite, Prism, PowerPoint, electronic lab notebooks, and in vivo data management platforms
• Ability to follow instructions and work independently
• Ability to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines
• Preferred experience with liquid handling equipment, flow cytometry, automation, and In Vivo Imaging System
• Must have excellent troubleshooting, organization, and planning skills, and the ability to work under timeline in a fast paced environment
• Excellent written and oral communication skills
• Be an integral part of a team to achieve organizational goal
• Communicate transparently to all stakeholders with relevant…