Scientist Antibody Discovery
Job in
South San Francisco, San Mateo County, California, 94083, USA
Listed on 2026-01-12
Listing for:
Global Channel Management, Inc
Full Time
position Listed on 2026-01-12
Job specializations:
-
Research/Development
Research Scientist, Biotechnology, Drug Discovery, Biomedical Science -
Science
Research Scientist, Biotechnology, Drug Discovery, Biomedical Science
Job Description & How to Apply Below
About the job Scientist Antibody Discovery
Scientist Antibody Discovery needs significant experience in antibody discovery and protein engineering by using single B cell cloning, hybridoma, or phage/yeast display techniques
Scientist Antibody Discovery requires:- PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience (preferably in industry)
- MS with 8+ years of research experience
- BS with 10+ years of research experience in antibody or protein engineering
- Strong background in molecular biology, antibody and protein expression, and biophysical characterization of recombinant antibodies and proteins
- Demonstrated experience in working collaboratively across various scientific disciplines and other parts of the organization to meet end goals
- Highly motivated individual with exceptionally good organizational skills, and attention to details
- Experience in single domain antibodies, multi-specific antibody engineering, Fc engineering, antibody drug conjugates, naïve phage or yeast display library design
- Experience in NGS analysis for antibody discovery and engineering
- Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry
- Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display
- Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits
- Rank-order clones by affinity, in vitro potency, and early develop ability assessment
- Execute sequence optimization of lead antibodies to improve develop ability and binding affinity
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