Scientist - III; Senior
Job in
South San Francisco, San Mateo County, California, 94083, USA
Listed on 2026-10-09
Listing for:
The Fountain Group
Full Time
position Listed on 2026-10-09
Job specializations:
-
Research/Development
Research Scientist, Biotech Research, Drug Discovery, Biomedical Science
Job Description & How to Apply Below
Scientist - III (Senior)
Location: South San Francisco, CA
Pay Rate: $76.97/hr.
Duration: 6 Months
- Execute and troubleshoot molecular interaction studies supporting antibody discovery, hit identification, lead optimization, and candidate selection.
- Generate and analyze binding affinity, kinetics, avidity, epitope binning, competition, and develop ability data for antibodies, bispecifics, and other biologics.
- Operate and optimize molecular interaction platforms including SPR, Carterra, Biacore, BLI, KinExA, and related technologies.
- Perform protein characterization and quantitative analysis of protein-protein interactions.
- Design assay plans, establish appropriate controls, and interpret complex interaction data to support discovery decisions.
- Optimize assay workflows for robustness, throughput, data quality, and turnaround time.
- Troubleshoot assay and instrument issues and support protocol, analysis template, and workflow development.
- Document experimental methods, results, data quality assessments, and conclusions in laboratory systems and technical reports.
- Support data analysis, visualization, and workflow improvements for molecular interaction studies.
- Master's degree in Biophysics, Biochemistry, Chemistry, Molecular Biology, Protein Sciences, Biomedical Engineering, or related field with 5+ years of hands-on experience
. - PhD in a related field preferred with 3+ years of hands-on experience
.
- Biomolecular interactions
- Protein characterization
- Protein-protein interaction analysis
- Surface Plasmon Resonance (SPR)
- Carterra
- Biacore
- Bio-Layer Interferometry (BLI)
- KinExA
- Binding affinity and kinetic analysis
- Antibody/protein interaction assays
- Molecular interaction data analysis
Assay troubleshooting - Quantitative data interpretation
- Therapeutic antibody discovery
- Bispecific antibody characterization
- Epitope binning
- Competition assays
- Cell binding characterization
- Receptor pharmacology
- Develop ability assessment
- Antibody engineering
- Fc biology
- Protein structure-function analysis
- Flow cytometry
- High-throughput screening
- Laboratory automation
- Python
- R
- Spotfire
Position Requirements
10+ Years
work experience
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