Senior Project Manager, Biologics R&D - Early Pipeline Programs

About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development.

Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

About the Role

We are seeking a Project Manager, Biologics R&D to support the planning and coordination of biologics programs and projects across our early pipeline, beginning with one of our prioritized programs and spanning additional discovery-stage programs, from early-stage discovery through lead optimization and lead selection, with growing support into IND-enabling studies as programs advance. This role is well-suited for a candidate with a strong scientific background who has transitioned into a project or program management role or who has taken on cross-functional project management responsibilities within research settings.

The ideal candidate will have hands‑on experience in biologics R&D, with the ability to manage timelines, track deliverables, and partner closely with scientific leads to keep projects moving forward. You will partner closely with Program Team Leads, who own program strategy and scientific direction, and your counterpart on the lead program to ensure consistent program management practices across the portfolio.

This position emphasizes scientific understanding, team coordination, and milestone tracking, making it a strong fit for someone with a bench science background who has taken on increasing responsibility for project organization and cross-functional collaboration. This role is as comfortable managing single projects as they are multiple projects driving to the same program objective or milestone.

Project Planning and Execution

• Support day-to-day planning and coordination of biologics research programs, ensuring execution of key activities from discovery through lead selection and into IND-enabling work as programs advance.
• Build and maintain project timelines that capture critical path, major milestones, dependencies, and deliverables across multiple concurrent programs at different stages of maturity.
• Partner with scientific leads and functional stakeholders to align on scope, priorities, resources and progress.

Milestone Management & Decision Support

• Collaborate with scientific teams to define key project milestones, decisional experiments and translate into actionable, resource-informed timelines, including stage-transition criteria such as hit-to-lead and lead selection.
• Help compile project data, timelines, risks, value-realization, and trade-offs to support informed decision-making.
• Coordinate and facilitate planning and documentation of decisive experiments, and update project plans based on results and next steps.

Cross-Functional Project Coordination

• Facilitate cross-functional collaboration across research to ensure effective communication and documentation of decisions, alignment of priorities and timelines.
• Schedule and run cross-functional meetings, ensuring clear agendas, effective documentation, and follow-up on action items.
• Monitor interdependencies across functions and proactively identify, flag and resolve conflicts across work streams.
• Coordinate outsourced work streams with CROs/CDMOs where…