Computational Scientist III

This range is provided by Orion Group. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

$75.00/hr - $78.00/hr

Direct message the job poster from Orion Group
Hybrid or remote out of South San Francisco
1 year initial contract with possibility of extension
$75 - $78/hr with medical benefits available at a cost

Orion Group and our largest US client are teaming up this holiday season for an exciting contract opportunity for a Computational Scientist. Our client is seeking candidates with a background in Computational Biology and advanced knowledge and experience analyzing spatial transcriptomics and proteomics data generated on the Cos Mx SMI and Pheno Cycler Fusion platforms.

Apply today and head into the new year as a part of a market leading pharmaceutical company.

The Precision Medicine Pathology team drives the scientific strategy for translational tissue‑based biomarker development & discovery target validation/MOA projects, leads pathology collaborative programs, conducts histopathological evaluation & analysis of IHC & spatial biology technologies, and provides technical/scientific leadership to histotechnicians & pathology scientists.

The successful candidate will have advanced knowledge and experience analyzing spatial transcriptomics and proteomics data generated on the Cos Mx SMI and Pheno Cycler Fusion platforms.

• Implementation of different scripts and pipelines for spatial transcriptomics data analysis and analysis of high‑plex Pheno Cycler Fusion (CODEX) images.
• Independently performing end‑to‑end high‑plex image analysis (tissue classification, cell segmentation, detection of marker positivity, cell phenotyping, unsupervised clustering, neighborhood analysis, proximity analysis).
• Acting as a subject matter resource and training other team members in spatial analysis tasks.
• Collaborating with pathologists and digital pathology scientists to support spatial biology projects.
• Presenting the results and findings from spatial biology studies to stakeholders.

• MSc, PhD, or equivalent degree in biological sciences / computational biology / engineering / computer science / informatics
• Fluency in Python and R is a must have
• Experience analyzing spatial transcriptomics and proteomics data generated on the Cos Mx is a must have
• Experience in implementing and utilizing open‑source scripts and pipelines for high‑plex image analysis
• Experience in quantitative digital pathology analysis platforms such as Halo, Visiopharm, Qu Path
• Close familiarity with tissue microscopic anatomy and histology (normal and diseased) is a plus
• Excellent verbal communication skills are required including the demonstrated ability to effectively and clearly summarize results for presentation and report generation
• Strong motivation, attention to detail, ability to think independently and fully integrate into a high achieving team environment
• Ability to multi‑task and manage multiple projects

Our role in supporting diversity and inclusion

As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion.

In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.

Mid‑Senior level

Contract

Science

Medical insurance
Vision insurance
401(k)